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Blasticidin A

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Formula: C58H107 N O23
CAS: 100513-53-9
search Element: blasticidin
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Identification

Structural Formula
Blasticidin A
CAS:
100513-53-9
EINECS:
Molecular Formula:
C58H107 N O23
MDL:
MFCD01770492
SMILES:
CCCCCCCCCCC(CC1(C(C(C(C(O1)CC(C(C(C(C(CC(CC(CC(CC(C(C)C(C(C)C(CC(C(C)C(C(CC(C)CC(C)/C=C(C)/C(=O)C2=C(N(CC2=O)C)O)O)O)O)O)O)O)O)O)O)O)O)O)O)O)O)O)O)O)O
Synonym:
2,4-Pyrrolidinedione,1-methyl-3-[(4S,6R)-1,8,9,11,13,15,17,19,21,23,25,26,27,28,29-pentadecahydroxy-2,4,6,10,14,16-hexamethyl-30-[(2R,3S,4S,5S,6S)-tetrahydro-3,4,5,6-tetrahydroxy-6-[(2R)-2-hydroxydodecyl]-2H-pyran-2-yl]-2-triacontenylidene]-(9CI) ; Blasticidin A ; (+)-Blasticidin A ; 2,4-Pyrrolidinedione,1-methyl-3-[(2E,4S,6R,8R,9R,10S,11R,13S,14S,15R,16S,17R,19R,21S,23S,25S,26S,27R,28R,29S)-1,8,9,11,13,15,17,19,21,23,25,26,27,28,29-pentadecahydroxy-2,4,6,10,14,16-hexamethyl-30-[(2R,3S,4S,5S,6S)-tetrahydro-3,4,5,6-tetrahydroxy-6-[(2R)-2-hydroxydodecyl]-2H-pyran-2-yl]-2-triaconten-1-ylidene]-,(3Z)-


Description

Blasticidin A, an antibiotic produced by Streptomyces, has been shown to have strong inhibitory activity toward aflatoxin production by Aspergillus parasiticus. This inhibition of aflatoxin production does not have a strong growth suppressing impact toward the aflatoxin-producing fungi. There was a decrease in abundance of ribosomal protein observed in Blasticidin A treated A. parasitici. Experiments indicate that Blasticidin A significantly reduced the expression of genes encoding aflatoxin regulatory gene and biosynthetic enzymes (omtA, ver-1, and pksA) in A. parasiticus.


Suppliers

Santa Cruz Biotechnology, Inc.
202082
Dayang Chem (Hangzhou) Co.,Ltd.
DC8063224
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Prices & Availability




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Properties for Blasticidin A

Molecular Weight:
1186.5 g·mol−1
Density:
1.32 g/cm3 (Predicted)
Boiling point:
1313.44° C at 760 mmHg (Predicted)
Solubility:
Soluble in DMSO, DMF, methanol, water (Fairly soluble), and ethanol (Fairly soluble).
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Safety & Transport Information

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Alternative Distributors of [Blasticidin A]

Producers or manufacturers change the product range from time to time. The following companies
have appeared as suppliers in the past / currently not verified

Cfm Oskar Tropitzsch GmbH | Clearsynth Canada INC.

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