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Blasticidin S Hydrochloride

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Formula: C17H26 N8 O5
CAS: 2079-00-7

Identification

Structural Formula
Blasticidin S Hydrochloride
CAS:
2079-00-7
EINECS:
Molecular Formula:
C17H26 N8 O5
MDL:
SMILES:
CN(CC[C@H](CC(=O)N[C@H]1C=C[C@@H](O[C@@H]1C(=O)O)N2C=CC(=NC2=O)N)N)C(=N)N.Cl
Synonym:
cytovirin ; blasticidins (6ci,8ci) ; bab ; blastizidin ; d-erythro-hex-2-enopyranuronic acid,4-[3-amino-5-(1-methylguanidino)valeramido]-1-(4-amino-2-oxo-1(2h)-pyrimidinyl)-1,2,3,4-tetradeoxy-(7ci) ; toabla-s ; bcs-3 ; blasticidin ; bla-s ; blaes ; babs ; bcs-3、bla-s ; blas


Description

Blasticidin S Hydrochloride, like puromycin, belongs to a group of cytosine amino nucleoside antibiotics. Blasticidin S is isolated from Streptomyces griseochromogenes and inhibits protein synthesis in both prokaryotic and eukaryotic cells, it acts quickly by inhibiting peptide bond formation by the ribosome.

The blasticidin S resistance gene (BSR), found in Bacillus cereus K55-S1, has been used in multiple studies for its use as a selective compound. Resistance is conferred by expression of one of two Blasticidin S deaminase genes: BSD from Aspergillus terreus or bsr from Bacillus cereus. These deaminases convert Blasticidin S to a nontoxic deaminohydroxy derivative.


Suppliers

Aozeal Certified Standards (AOCS), Inc.
B0149.00
Indofine Chemical Co, Inc.
Bio-562
Santa Cruz Biotechnology, Inc.
204655
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CAS equal suppliers

Blasticidin-S
Chemieliva Pharmaceutical Co., Ltd.
CP4551365
Blasticidin-S
Dayang Chem (Hangzhou) Co.,Ltd.
DC4031612
Blasticidin-S
Haihang Industry Co., Ltd.
HI3381014

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Properties for Blasticidin S Hydrochloride

Molecular Weight:
422.51 g·mol−1
Density:
1.61 g/cm3
Melting point:
235-236°C
Solubility:
Solubility.: in water >30 g/l (20°C). In acetic acid >30 g/l (20°C). Practically insoluble in acetone, benzene, carbon tetrachloride, chloroform, cyclohexane, dioxane, ethanol diethyl ether, ethyl acetate, methanol, pyridine, xylene.
Physical Description:
colourless needles
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Safety & Transport Information

Poison by ingestion, skin contact, and intravenous routes. When heated to decomposition it emits toxic fumes of NOx. See other blastomycin entries.
Risk Codes:
R28 - Very toxic if swallowed
Safety Codes:
S24/25 - Avoid contact with skin and eyes
S36/37 - Wear suitable protective clothing and gloves
S45 - In case of accident or if you feel unwell seek medical advice immediately (show the label where possible)
Hazard Classes:
6.1(a)
Hazard Symbols:
T+
Hazard symbol T+
RID/ADR certification :
3172
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Alternative Distributors of [Blasticidin S Hydrochloride]

Producers or manufacturers change the product range from time to time. The following companies
have appeared as suppliers in the past / currently not verified

Discovery Fine Chemicals Limited | Jinan Haohua Industry Co., Ltd.

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