4-[(1E,3S,5Z,8R/S,10S)-3,11-Bis-{[tert-butyl(dimethyl)silyl]oxy}-2,6,10-trimethyl-undeca-1,5-dienyl]-2-methyl-1,3-thiazole | CAS 210690-85-0

Element: trimethyl dimethyl thiazole dienyl methyl undeca butyl silyl tert

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C-S » Chemicals » bis-tert-butyl-dimethyl-silyl-oxy-trimethyl-undeca-dienyl-methyl-thiazole-PX71589

Identification

4-[(1E,3S,5Z,8R/S,10S)-3,11-Bis-{[tert-butyl(dimethyl)silyl]oxy}-2,6,10-trimethyl-undeca-1,5-dienyl]-2-methyl-1,3-thiazole

CAS:

210690-85-0

EINECS:

Molecular Formula:

C₃₀H₅₇NO₂SSi₂

MDL:

SMILES:

C[C@@H](CCCC(C)=C/C[C@H](O[Si](C)(C)C(C)(C)C)C(C)=CC1=CSC(C)=N1)CO[Si](C)(C)C(C)(C)C

Synonym:

4-[(1e,3s,5z,10s)-3,11-bis[[(1,1-dimethylethyl)dimethylsilyl]oxy]-2,6,10-trimethyl-1,5-undecadien-1-yl]-2-methyl-thiazole ; 4-[(1e,3s,5z,8r/s,10s)-3,11-bis-{[tert-butyl(dimethyl)silyl]oxy}-2,6,10-trimethyl-undeca-1,5-dienyl]-2-methyl-1,3-thiazole

Description

Intermediary obtained in the synthesis of members of the Epothilone family, polyketide natural products that inhibit cancer cells via a mechanism similar to Paclitaxel. Also found to be effective against Paclitaxel-resistant tumors. Epothilone D is currently in Phase I of clinical testing.

Suppliers

Santa Cruz Biotechnology, Inc.

206784

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CAS equal suppliers

4-[(1E,3S,5Z,10S)-3,11-bis[(tert-butyldimethylsilyl)oxy]-2,6,10-trimethylundeca-1,5-dien-1-yl]-2-methyl-1,3-thiazole

Santa Cruz Biotechnology, Inc.

SCB55680222720

(2S,6Z,9S,10E)-1,9-bis[(1,1-dimethylethyl)dimethylsilyloxy]-11-(2-methylthiazol-4-yl)-2,6,10-trimethyl-undeca-6,10-diene

Chemlyte Solutions

CS3240097200

Prices & Availability

Data is processed

Properties for 4-[(1E,3S,5Z,8R/S,10S)-3,11-Bis-{[tert-butyl(dimethyl)silyl]oxy}-2,6,10-trimethyl-undeca-1,5-dienyl]-2-methyl-1,3-thiazole

Molecular Weight:

552.01508 g·mol−1

Safety & Transport Information

coming up soon

Alternative Distributors of [4-[(1E,3S,5Z,8R/S,10S)-3,11-Bis-{[tert-butyl(dimethyl)silyl]oxy}-2,6,10-trimethyl-undeca-1,5-dienyl]-2-methyl-1,3-thiazole]

Producers or manufacturers change the product range from time to time. Currently there are no other manufacturers known.

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Mol File:

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MSDS:

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4-[(1E,3S,5Z,8R/S,10S)-3,11-Bis-{[tert-butyl(dimethyl)silyl]oxy}-2,6,10-trimethyl-8-(phenylsulfonyl)undeca-1,5-dienyl]-2-methyl-1,3-thiazole