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4-[(1E,3S,5Z,8R/S,10S)-3,11-Bis-{[tert-butyl(dimethyl)silyl]oxy}-2,6,10-trimethyl-8-(phenylsulfonyl)undeca-1,5-dienyl]-2-methyl-1,3-thiazole

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Formula: C36H61NO4S2Si2
CAS: 308357-81-5
search Element: phenylsulfonyl trimethyl dimethyl thiazole dienyl methyl undeca butyl silyl tert
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Identification

Structural Formula
4-[(1E,3S,5Z,8R/S,10S)-3,11-Bis-{[tert-butyl(dimethyl)silyl]oxy}-2,6,10-trimethyl-8-(phenylsulfonyl)undeca-1,5-dienyl]-2-methyl-1,3-thiazole
CAS:
308357-81-5
EINECS:
Molecular Formula:
C36H61NO4S2Si2
MDL:
SMILES:
C[C@H](CO[Si](C)(C)C(C)(C)C)CC(CC(C)=C/C[C@H](O[Si](C)(C)C(C)(C)C)C(C)=CC1=CSC(C)=N1)S(=O)(=O)C1=CC=CC=C1
Synonym:


Description

Intermediary obtained in the synthesis of members of the Epothilone family, polyketide natural products that inhibit cancer cells via a mechanism similar to Paclitaxel. Also found to be effective against Paclitaxel-resistant tumors. Currently in Phase I of clinical testing.


Suppliers

Santa Cruz Biotechnology, Inc.
206783
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CAS equal suppliers

4-[(1E,3S,5Z,8R/S,10S)-3,11-Bis-{[tert-butyl(dimethyl)silyl]oxy}-2,6,10-trimethyl-8-(phenylsulfonyl)undeca-1,5-dienyl]-2-methyl-1
Santa Cruz Biotechnology, Inc.
sc-206783

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Properties for 4-[(1E,3S,5Z,8R/S,10S)-3,11-Bis-{[tert-butyl(dimethyl)silyl]oxy}-2,6,10-trimethyl-8-(phenylsulfonyl)undeca-1,5-dienyl]-2-methyl-1,3-thiazole

Molecular Weight:
692.17 g·mol−1
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Safety & Transport Information

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Alternative Distributors of [4-[(1E,3S,5Z,8R/S,10S)-3,11-Bis-{[tert-butyl(dimethyl)silyl]oxy}-2,6,10-trimethyl-8-(phenylsulfonyl)undeca-1,5-dienyl]-2-methyl-1,3-thiazole]

Producers or manufacturers change the product range from time to time. Currently there are no other manufacturers known.
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