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(+)-Bicuculline

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Formula: C20H17NO6
CAS: 485-49-4
search Element: bicuculline
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Identification

Structural Formula
(+)-Bicuculline
CAS:
485-49-4
EINECS:
207-619-7
Molecular Formula:
C20H17NO6
MDL:
MFCD00005006
SMILES:
CN1CCC2=CC3=C(C=C2[C@H]1[C@H]4C5=C(C6=C(C=C5)OCO6)C(=O)O4)OCO3
Synonym:
bicucullin ; bicuculline ; (+)-bicuculine ; bucuculline ; d-bicuculline ; plus-bicuculline ; nsc 3219 ; nsc 32192) ; (+)-bicuculline


Description

(+)-Bicuculline is an antagonist of the GABAA receptor. (+)-Bicuculline is the parent compound of the water soluble N-methyl derivatives (-)-Bicuculline methiodide and (-)-Bicuculline methobromide. Antagonism of the GABAA receptor by (+)-Bicuculline blocks the neurotransmission inhibition function of the GABA system in vitro.


Suppliers

Autech Industry Co.,Limited
AIC4051620
+
Ambeed, Inc.
A658573
+
Chengdu Pufeide Biotech. Co., Ltd
CPB4951980
+
Conscientia Industrial Co., Ltd (Zhejiang Conscientia Pharmaceutical)
CI10354140
+
Chemlyte Solutions
CS270810
+
Chemvon Biotechnology Co. Ltd.
CBC4501800
+
CSNpharm, Inc.
CSN10435
Hangzhou Lingrui Chemical Co., Ltd.
HLC5252100
+
Pharmacore Co., Limited
PL3451035
CM Fine Chemicals
CFC2551020
Leap Chem Co., Ltd
LC270810
+
Santa Cruz Biotechnology, Inc.
202498
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CAS equal suppliers

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Dayang Chem (Hangzhou) Co.,Ltd.
DC9303720
(D)-Bicuculline
Carbone Scientific Co., Ltd.
CS8402520
(D)-Bicuculline
Haihang Industry Co., Ltd.
HI7802340
(D)-Bicuculline
Gihi Chemicals Co., Limited
GCL8103240
(R-(R*,S*))-6-(5,6,7,8-Tetrahydro-6-methyl-1,3-dioxolo(4,5-g)isoquinolin-5-yl)-furo(3,4-e)-1,3-benzodioxol-8(6H)-one
Salsbury Chemicals, Inc.
SC47328141984

Prices & Availability




Data is processed


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Properties for (+)-Bicuculline

Molecular Weight:
367.35 g·mol−1
Density:
1.47 g/cm3 (Predicted)
Melting point:
193-197 °C
Boiling point:
542.33° C at 760 mmHg (Predicted)
Solubility:
Soluble in water (partly), chloroform (1 mg/ml), ethyl acetate, benzene, DMSO (100 mM), ethanol (5 mM), ether (sparingly), and alcohol.
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Safety & Transport Information

Risk Codes:
R20/21/22 - Harmful by inhalation, in contact with skin and if swallowed
R23/24/25 - Toxic by inhalation, in contact with skin and if swallowed
R36/37/38 - Irritating to eyes, respiratory system and skin
R50 - Very toxic to aquatic organisms
Safety Codes:
S26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice
S36 - Wear suitable protective clothing
S36/37 - Wear suitable protective clothing and gloves
S45 - In case of accident or if you feel unwell seek medical advice immediately (show the label where possible)
S61 - Avoid release to the environment. Refer to special instructions/safety data sheet
Hazard Classes:
6.1(b)
Hazard Symbols:
T, N, Xn
Hazard symbol T Hazard symbol N Hazard symbol Xn
Storage temperature :
0-6°C
RID/ADR certification :
UN 1544 6.1 / PG 2
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Alternative Distributors of [(+)-Bicuculline]

Producers or manufacturers change the product range from time to time. The following companies
have appeared as suppliers in the past / currently not verified

Biosynth AG | BOC Sciences | Share Chemical Co., Ltd. | Jinan Great Chemical Co., Ltd. | BioBioPha Co., Ltd. | Molekula GmbH | Shanghai PI Chemicals Ltd. | Clearsynth Canada INC. | Shanghai Yingxuan Chempharm Co., Ltd. | ShangHai Biochempartner Co., Ltd.

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Downloads

Mol File:
-/-
MSDS:
-/-




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