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Aurora Kinase Inhibitor III

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Formula: C21H18 F3 N5 O
CAS: 879127-16-9
search Element: inhibitor aurora kinase
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Identification

Structural Formula
Aurora Kinase Inhibitor III
CAS:
879127-16-9
EINECS:
Molecular Formula:
C21H18 F3 N5 O
MDL:
SMILES:
C1CC1C(=O)NC2=CC=CC(=C2)NC3=NC=CC(=N3)NC4=CC=CC(=C4)C(F)(F)F
Synonym:
aurora kinase inhibitor iii ; cyclopropanecarboxylic acid {3-[4-(3-trifluoromethyl-phenylamino)-pyrimidin-2-ylamino]-phenyl}-amide ; cyclopropanecarboxamide,n-[3-[[4-[[3-(trifluoromethyl)phenyl]amino]-2-pyrimidinyl]amino]phenyl]- ; inh 1


Description

Aurora kinase inhibitor III is a potent ATP-competitive aurora related kinase (also designated ARK) inhibitor. Aurora kinase inhibitor III is a cell-permeable, 2,4-dianilinopyrimidine compound which has been used to study a variety of tumor types. Aurora kinase protein levels are elevated in c-myc-driven B-cell lymphomas in both mice and humans; study of the inhibition of Aurora kinase proteins could lead to potential treatments for malignancies.


Suppliers

Aea.ltd
A7561512
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Santa Cruz Biotechnology, Inc.
203828
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CAS equal suppliers

N-[3-[[4-[3-(trifluoromethyl)anilino]pyrimidin-2-yl]amino]phenyl]cyclopropanecarboxamide
Manchester Organics Limited
T34126

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Properties for Aurora Kinase Inhibitor III

Molecular Weight:
413.401 g·mol−1
Solubility:
Soluble in DMSO or EtOH
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Safety & Transport Information

Storage temperature :
2-8°C
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Alternative Distributors of [Aurora Kinase Inhibitor III]

Producers or manufacturers change the product range from time to time. Currently there are no other manufacturers known.
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Downloads

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MSDS:
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