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Amlodipine

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Formula: C26H31ClN2O8S
CAS: 88150-42-9
search Element: amlodipine

Identification

Structural Formula
Amlodipine
CAS:
88150-42-9
EINECS:
Molecular Formula:
C26H31ClN2O8S
MDL:
MFCD00887594
SMILES:
CCOC(=O)C1=C(NC(=C(C1C2=CC=CC=C2Cl)C(=O)OC)C)COCCN
Synonym:
lotrel ; isti ; amlopres ; uk-48340-11 ; besylate ; amlodipine ; uk-48340 ; amlodipin ; intervask ; pelmec


Description

Amlodipine is a long-acting dihydropyridine, L-type, calcium channel protein inhibitor and blocker. Amlodipine belongs to a class of cardiovascular drugs, which act at the voltage gated calcium channel of the CaV1, or L-type, class. Amlodipine has been shown to have antihypertensive and antianginal effects. Its activity resides mainly in the (-)-isomer. Amlodipine inhibits growth of human epidermoid carcinoma A431 cells.


Suppliers

Shandong Ench Chemical Co.,Ltd
SECC3001500
Chemlyte Solutions
CS180540
Autech Industry Co.,Limited
AIC2701080
Aozeal Certified Standards (AOCS), Inc.
A0009.00
Conscientia Industrial Co., Ltd (Zhejiang Conscientia Pharmaceutical)
CI6902760
IBIS Chemie International
ICI2501000
BoomKing Industrial Co.,Limited
BIC3101240
Aecochem Corp.
AC140420
CSNpharm, Inc.
CSN16790
Hangzhou Keying Chem Co., Ltd.
HKC3001200
scienTEST - bioKEMIX GmbH
S-B2501000
Finetech Industry Limited
FIL2501000
Leap Chem Co., Ltd
LC180540
Santa Cruz Biotechnology, Inc.
200195
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CAS equal suppliers

(S)-Amlodipine
Xiamen Equation Chemical Co.,Ltd
XECC8964480
Amlodipine Base
Molekula
40403726
Amlodipine, 97+%
Alfa (A Johnson Matthey Company)
A5121536
3-Ethyl 5-methyl 2-[(2-aminoethoxy)methyl]-4-(2-chlorophenyl)-6-methyl-1,4-dihydropyridine-3,5-dicarboxylate
BLD Pharmatech Ltd
BP2332869984
2-[(2-Aminoethoxy)methyl]-4-(2-chlorophenyl)-1,4-dihydro-6-methyl-3,5-pyridinedicarboxylic acid 3-ethyl 5-methyl ester
Gihi Chemicals Co., Limited
GCL44604178416

Prices & Availability




Data is processed


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Properties for Amlodipine

Molecular Weight:
567.05 g·mol−1
Density:
~1.2 g/cm3 (Predicted)
Melting point:
178-179 °C
Boiling point:
~527.16° C at 760 mmHg (Predicted)
Solubility:
Soluble in DMSO (25 mg/mL), ethanol (25 mg/mL), water (75.3 mg/mL), DMF (25 mg/mL), acetone, chloroform, ethyl acetate, and methanol.
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Hazard Statements

GHS05

GHS05
Corrosive
  • Corrosive to metals, category 1
GHS06

GHS06
Toxic
  • Acute toxicity (oral, dermal, inhalation), categories 1, 2, 3
GHS08

GHS08
Health hazard
  • Respiratory sensitization, category 1
  • Germ cell mutagenicity, categories 1A, 1B, 2
  • Carcinogenicity, categories 1A, 1B, 2
  • Reproductive toxicity, categories 1A, 1B, 2
  • Specific target organ toxicity following single exposure, categories 1, 2
  • Specific target organ toxicity following repeated exposure, categories 1, 2
  • Aspiration hazard, categories 1, 2
GHS09

GHS09
Environmental hazard
  • Acute hazards to the aquatic environment, category 1
  • Chronic hazards to the aquatic environment, categories 1, 2
  • Environmental toxicity, categories 1, 2

Safety & Transport Information

Hazard Classes:
irritant
Storage temperature :
-20 °C Freezer
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Alternative Distributors of [Amlodipine]

Producers or manufacturers change the product range from time to time. The following companies
have appeared as suppliers in the past / currently not verified

Inter-Chemical Ltd. | Chemwerth Inc. | Anhui Worldbest Import and Export Co., Ltd. | Hallochem Pharma Co., Ltd. | Shanghai Eagle Chemical Co., Ltd. | 3B Scientific Corporation | Jinan Jinao Chemical Development Co., Ltd. | Qichun QiLong Chemical Co., Ltd. | Zhejiang Materials Industry Chemical Group Co., Ltd. | Synfine Research Inc. | Hefei Photochem Trading Co., Ltd | New Dragon Industrial Co., Ltd | Jinan Victory Imp. & Exp. Co., Ltd. | Hana Pharm. Co., Ltd. | Conier Chem & Pharma Ltd | ShangHai Biochempartner Co., Ltd. | Chengdu Qiaofeng Technological Development Co., Ltd. | Shanghai AOKChem Group Limited | Carbone Scientific Co., Ltd. | Qingdao Sunrisechem Co., Ltd. | Kinfon Pharmaceutical and Chemical Service Co., Ltd. | Lanospharma Laboratories Co., Ltd. | TCS INDUSTRY LTD. | Jinan Great Chemical Co., Ltd. | Bichem Lab Co., Ltd. | East Chemical Industry Co., Ltd. | Medilink Pharmachem | Watson International Ltd | BOC Sciences | Hubei Yuancheng Saichuang Tech.Co.,Ltd | Jinan Haohua Industry Co., Ltd. | Finetech Industry Limited | Xiamen Hisunny Chemical Co., Ltd. | scienTEST | Gihi Chemicals Co., Limited | Clearsynth Canada INC. | Nebula Chemicals Co, Ltd. | Wanko Chemical Co., Ltd. | Haihang Industry Co., Ltd.

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