Amlodipine besylate | CAS 111470-99-6

Element: amlodipine besylate

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C-S » Chemicals » amlodipine-besylate-PX81338

Identification

Amlodipine besylate

CAS:

111470-99-6

EINECS:

Molecular Formula:

C₂₀H₂₅ClN₂O₅.C₆H₆O₃S

MDL:

MFCD00887594

SMILES:

CCOC(=O)C1=C(NC(=C(C1C2=CC=CC=C2Cl)C(=O)OC)C)COCCN.C1=CC=C(C=C1)S(=O)(=O)O

Synonym:

amdipin ; amdepin ; amlor ; vazkor ; norvas ; amcard ; norvasc ; amlodin ; lowrac ; amlopin

Description

Amlodipine besylate is an L-type calcium channel protein inhibitor and blocker that contains antihypertensive properties. Amlodipine besylate also displays vasoprotective effects in cardiovascular disease and inhibits Ca²⁺-induced contractions in depolarized rat aorta (IC₅₀ = 1.9 nM). Amlodipine besylate has been shown to inhibit proliferation of human vascular smooth muscle cells and epidermoid carcinoma A431 cells (IC₅₀ = 25 μM).

Suppliers

Chemlyte Solutions

CS6842052

Aozeal Certified Standards (AOCS), Inc.

A0009.02

Conscientia Industrial Co., Ltd (Zhejiang Conscientia Pharmaceutical)

CI262210488

Shandong SanYoung Industry Co., Ltd

SSI13305320

R.J. Chemicals, Inc.

RC7602280

INDAM Inc.

I380760

Jai Radhe Sales

JRS5702280

IBIS Chemie International

ICI9503800

Xiamen Equation Chemical Co.,Ltd

XECC12166080

Sancai Industry Co.,Ltd.

SIC9123648

Aecochem Corp.

AC5321596

CSNpharm, Inc.

CSN13575

scienTEST - bioKEMIX GmbH

S-B9503800

Carbone Scientific Co., Ltd.

CS10643192

AK Scientific, Inc.

AS7222166

Xingrui Industry Co., Limited

XIL11024408

Santa Cruz Biotechnology, Inc.

203511

Dayang Chem (Hangzhou) Co.,Ltd.

DC11784712

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CAS equal suppliers

Amlodipine Besilate

Pharmaffiliates Analytics & Synthetics Pvt. Limited

PA 01 50000

Amlodipine besylate, 98+%

Alfa (A Johnson Matthey Company)

A16004800

Amlodipine benzenesulfonate

Chemieliva Pharmaceutical Co., Ltd.

CP18905670

Amlodipine benzenesulfonate

Leap Chem Co., Ltd

LC9722916

Amlodipine benzenesulfonate

Hangzhou J&H Chemical Co., Ltd.

HJC16746696

Amlodipine benzenesulfonate

Sigma-Aldrich International GmbH

SI17285184

Amlodipine benzenesulfonate

Skyrun Industrial Co., Ltd.

SI14584374

Amlodipine benzenesulfonate

LGM Pharma

LP5401620

Amlodipine benzenesulfonate

Purestar Chem Enterprise Co., Ltd.

PCE18367344

Amlodipine benzenesulfonate

Huateng Pharmaceutical Co.,Ltd

817347

3-Ethyl 5-methyl 2-[(2-aminoethoxy)methyl]-4-(2-chlorophenyl)-6-methyl-1,4-dihydropyridine-3,5-dicarboxylate; benzenesulfonic acid

BLD Pharmatech Ltd

BP3276098280

2-(2-Aminoethoxymethyl)-4-(2-chlorophenyl)-6-methyl-1,4-dihydropyridine-3,5-dicarboxylic acid o3-ethyl ester o5-methyl ester; benzenesulfonic acid

Salsbury Chemicals, Inc.

SC63072189216

Prices & Availability

Data is processed

Properties for Amlodipine besylate

Molecular Weight:

567.05 g·mol−1

Melting point:

199-201 °C

Boiling point:

527.2° C at 760 mmHg (Predicted)

Solubility:

DMSO: 20 mg/mL

Safety & Transport Information

Risk Codes:

R20/21/22 - Harmful by inhalation, in contact with skin and if swallowed
R22 - Harmful if swallowed
R36/37/38 - Irritating to eyes, respiratory system and skin

Safety Codes:

S26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice
S36 - Wear suitable protective clothing

Hazard Symbols:

Storage temperature :

Store at RT

Alternative Distributors of [Amlodipine besylate]

Producers or manufacturers change the product range from time to time. The following companies
have appeared as suppliers in the past / currently not verified

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MSDS:

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R(+)Amlodipine Besylate

Amlodipine besylate, 98+%

Amlodipine Besylate EP Impurity D

Diethyl Amlodipine besylate salt impurity