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N-alpha-t-Butyloxycarbonyl-N-epsilon-benzyloxycarbonyl-D-lysine

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Formula: C19H28 N2 O6
CAS: 55878-47-2

Identification

Structural Formula
N-alpha-t-Butyloxycarbonyl-N-epsilon-benzyloxycarbonyl-D-lysine
CAS:
55878-47-2
EINECS:
Molecular Formula:
C19H28 N2 O6
MDL:
Synonym:
boc-d-lysine(cbz) ; nalpha-boc-nepsilon-z-d-lysine ; nsc 334941 ; n-alpha-boc-n-epsilon-benzyloxycarbonyl-d-lysine ; n2-[(1,1-dimethylethoxy)carbonyl]-n6-[(phenylmethoxy)carbonyl]-d-lysine ; (r)-6-(((benzyloxy)carbonyl)amino)-2-(((tert-butoxy)carbonyl)amino)-hexanoicacid ; boc-n-epsilon-z-d-lysine ; n-alpha-tert-butyloxycarbonyl-n-epsilon-benzyloxycarbonyl-d-lysine ; d-lysine,n2-[(1,1-dimethylethoxy)carbonyl]-n6-[(phenylmethoxy)carbonyl]- ; boc-d-lysine(z)-oh ; (r)-6-(((benzyloxy)carbonyl)amino)-2-(((tert-butoxy)carbonyl)amino)-hexanoic acid ; n-alpha-butoxycarbonyl-n-epsilon-carbobenzoxy-d-lysine


Description

Building block with side protection orthogonal to Fmoc/tBu strategy. Can be used for side specific derivatization, for example for TFA mediated in situ cyclization, which is taking advantage of intermediate aspartamide formation. Reference: A Tandem In Situ Peptide Cyclization through Trifluoroacetic Acid Cleavage; Koushik Chandra, Tapta Kanchan Roy, Deborah E. Shalev, Abraham Loyter, Chaim Gilon, R. Benny Gerber, and Assaf Friedler; Angew. Chem. Int. Ed. 2014; 53: 9450-9455. DOI: 10.1002/anie.201402789.


Suppliers

Iris Biotech GmbH
BAA1358
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Prices & Availability




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Properties for N-alpha-t-Butyloxycarbonyl-N-epsilon-benzyloxycarbonyl-D-lysine

Molecular Weight:
380.44 g·mol−1
Density:
1.176 g/cm3
Melting point:
71-77°C
Boiling point:
587°C at 760 mmHg
Flash point:
308.8°C
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Safety & Transport Information

Storage temperature :
Store at RT.
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Alternative Distributors of [N-alpha-t-Butyloxycarbonyl-N-epsilon-benzyloxycarbonyl-D-lysine]

Producers or manufacturers change the product range from time to time. Currently there are no other manufacturers known.
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MSDS:
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