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Zebularine

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Formula: C9H12N2O5
CAS: 3690-10-6
search Element: zebularine

Identification

Structural Formula
Zebularine
CAS:
3690-10-6
EINECS:
Molecular Formula:
C9H12N2O5
MDL:
MFCD04973699
SMILES:
C1=CN(C(=O)N=C1)C2C(C(C(O2)CO)O)O
Synonym:
2-pyrimidone-1-β-d-riboside ; pyrimidin-2-one beta-ribofuranoside ; 4-deoxyuridine ; nsc 309132 ; 1--d-ribofuranosyl-2(1h)-pyrimidinone ; 4-deoyuridine ; pyrimidin-2-one -d-ribofuranoside ; 2(1h)-pyrimidinone, 1-b-d-ribofuranosyl- ; pyrimidin-2-one beta-d-ribofuranoside ; 1-b-d-ribofuranosyl-2-(1h)-pyrimidinone


Description

Zebularine is a cell-permeable chemically stable cytidine analog and DNA methylation inhibitor which acts by forming a covalent complex with DNMT. It displays antiangiogenic activity and markedly inhibits vessel formation in different tumor models. It reactivates silenced E-cadherin and potentiates the effects of other epigenetic therapeutics such as vorinistat. Induces differentiation of mesenchymal cells into cardiomyocytes. Inhibits cytidine deaminase (CDD).


Suppliers

Ambeed, Inc.
A162514
Conscientia Industrial Co., Ltd (Zhejiang Conscientia Pharmaceutical)
CI6902760
Chemlyte Solutions
CS180540
CSNpharm, Inc.
CSN12234
Amadis Chemical Company Limited
ACCL3101550
Santa Cruz Biotechnology, Inc.
203315
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CAS equal suppliers

4-Deoxyuridine
Salsbury Chemicals, Inc.
SC3361008
Zebularine (4-Deoxyuridine)
Zhangjiagang Pharmabl Co., Ltd
ZP16204860
1-beta-D-Ribofuranosyl-2(1H)-pyrimidinone
Finipharma Ltd
F17223444
1-[(2R,4R,5R)-3,4-dihydroxy-5-(hydroxymethyl)oxolan-2-yl]-1,2-dihydropyrimidin-2-one
Shandong SanYoung Industry Co., Ltd
SSI38220152880

Prices & Availability




Data is processed


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Properties for Zebularine

Molecular Weight:
228.203 g·mol−1
Density:
1.73 g/cm3 (Predicted)
Melting point:
160-162 °C C
Boiling point:
499.02° C at 760 mmHg (Predicted)
Solubility:
DMSO: 16 mg/mL, soluble
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Safety & Transport Information

Storage temperature :
2-8°C
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Alternative Distributors of [Zebularine]

Producers or manufacturers change the product range from time to time. The following companies
have appeared as suppliers in the past / currently not verified

Clearsynth Canada INC. | Suzhou Rovathin Pharmatech Co., Ltd

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MSDS:
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