Zamifenacin fumarate | CAS 127308-98-9

Element: zamifenacin fumarate

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Identification

Zamifenacin fumarate

CAS:

127308-98-9

EINECS:

Molecular Formula:

C₂₇H₂₉NO₃.C₄H₄O₄

MDL:

MFCD09263617

SMILES:

C1C[C@H](CN(C1)CCC2=CC3=C(C=C2)OCO3)OC(C4=CC=CC=C4)C5=CC=CC=C5.C(=C/C(=O)O)C(=O)O

Synonym:

(3r)-1-[2-(1-,3-benzodioxol-5-yl)ethyl]-3-(diphenylmethoxy)piperidinefumarate ; zamifenacinfumarate

Description

Zamifenacin fumarate is a selective antagonist of mAChR M3 (pK_i values are 8.52, 7.93, 7.90 and 7.78 for mAChR M3, mAChR M2, mAChR M1 and mAChR M4 receptors, respectively). It displays higher affinity at ileal mAChR M3 (pK_i = 9.3) compared to oesophageal and tracheal mAChR M3 receptors (pK_i values are 8.8 and 8.2, respectively).

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Properties for Zamifenacin fumarate

Molecular Weight:

531.602 g·mol−1

Boiling point:

700.2°C at 760 mmHg

Flash point:

377.3°C

Solubility:

Soluble in ethanol (25 mM), and DMSO (100 mM).

Safety & Transport Information

Storage temperature :

Desiccate at +4 °C

Alternative Distributors of [Zamifenacin fumarate]

Producers or manufacturers change the product range from time to time. Currently there are no other manufacturers known.

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