xanthohumo ; 1-[2,4-dihydroxy-6-methoxy-3-(3-methyl-but-2-enyl)-phenyl]-3-(4-hydroxy-phenyl)-propenone ; (2e)-1-[2,4-dihydroxy-6-methoxy-3-(3-methyl-2-buten-1-yl)phenyl]-3-(4-hydroxyphenyl)-2-propen-1-one ; xanthohumol, humulus lu pulus ; 1-(2,4-dihydroxy-6-methoxy-3-(3-methylbut-2-en-1-yl)phenyl)-3-(4-hydroxyphenyl)prop-2-en-1-one ; 2',4',4-trihydroxy-6'-methoxy-3'-prenylchalcone ; xanthohumol ; xanthohumol from hop (humulus lupulus) ; 2-propen-1-one,1-[2,4-dihydroxy-6-methoxy-3-(3-methyl-2-buten-1-yl)phenyl]-3-(4-hydroxyphenyl)-,(2e)-
Description
Xanthohumol from hop (Humulus lupulus) has demonstrated antiproliferative and cytotoxic effects in human cancer cell lines. It has been shown to inhibit DGAT (diacylglycerol acetyltransferase) and human CYP (cytochrome P450 enzymes). It has also been shown to inhibit the expression of HIF-1α and VEGF under hypoxic conditions.
Xanthohumol from hop (Humulus lupulus) is an inhibitor of DNA Polymerase, VCP and PKB Kinase.
Properties for Xanthohumol from hop (Humulus lupulus)
Molecular Weight:
354.4 g·mol−1
Density:
1.244
Melting point:
157-159 °C
Boiling point:
576.5 °C at 760 mmHg
Solubility:
Soluble in ethanol (10 mg/mL), DMSO (25 mg/mL), methanol (10 mg/mL), and aqueous buffers (20 µM).
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Safety & Transport Information
Risk Codes:
R43 - May cause sensitisation by skin contact R50/53 - Very toxic to aquatic organisms, may cause long-term adverse effects in the aquatic environment
Safety Codes:
S22 - Do not breathe dust S45 - In case of accident or if you feel unwell seek medical advice immediately (show the label where possible) S60 - This material and its container must be disposed of as hazardous waste S61 - Avoid release to the environment. Refer to special instructions/safety data sheet
Hazard Symbols:
N, Xi
Storage temperature :
2-8°C
RID/ADR certification :
UN 3077 9 / PG 3
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Alternative Distributors of [Xanthohumol from hop (Humulus lupulus)]
Producers or manufacturers change the product range from time to time. Currently there are no other manufacturers known.
Element: 
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