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Tubulin Polymerization Inhibitor II

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Formula: C19H19NO5
CAS: 1151995-69-5
search Element: polymerization inhibitor tubulin
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Identification

Structural Formula
Tubulin Polymerization Inhibitor II
CAS:
1151995-69-5
EINECS:
Molecular Formula:
C19H19NO5
MDL:
SMILES:
COC1=CC2=C(C=C1)/C(=CC3=CC(=C(C(=C3)OC)OC)OC)/C(=O)N2
Synonym:


Description

Tubulin Polymerization Inhibitor II is a cell-permeable, SU5416 derived combretastatin A-4 analog that acts as an effective Tubulin inhibitor (IC50 = 4.5 μM in inhibiting polymerization of purified porcine brain tubulin). Tubulin Polymerization Inhibitor II has also been shown to exhibit extremely potent anti-proliferative activity towards various cancer cell lines (GI50 <10 nM for 46 lines among a 53 NCI panel tested).


Suppliers

Santa Cruz Biotechnology, Inc.
296673
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Prices & Availability




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Properties for Tubulin Polymerization Inhibitor II

Molecular Weight:
341.4 g·mol−1
Solubility:
DMSO (10 mg/ml)
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Alternative Distributors of [Tubulin Polymerization Inhibitor II]

Producers or manufacturers change the product range from time to time. Currently there are no other manufacturers known.
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