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Trolox

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Formula: C14H18O4
CAS: 53188-07-1
search Element: trolox

Identification

Structural Formula
Trolox
CAS:
53188-07-1
EINECS:
258-422-8
Molecular Formula:
C14H18O4
MDL:
MFCD00006846
SMILES:
CC1=C(C(=C2CCC(OC2=C1C)(C)C(=O)O)C)O
Synonym:
trolox ; trolox(r) ; trolox, 97% 5gr ; 6-hydroxy-2,5,7,8-tetramethylchroman-2-carboxylic acid ; trolox, 97% 1gr ; troloxtm c ; timtec-bb sbb005933 ; trolox(r),97% ; troloxc ; trolox tm


Description

Trolox is an antioxidant derived from water-soluble vitamin E, with oxygen quenching activity. The activity of Trolox ranges between ferulic acid and p-coumaric acid. Studies show that lipid peroxidation, cytotoxicity, and apoptosis induced by cytochrome P450 2E1 in Hep G2 cells is blocked in the presence of Trolox. It has been observed that Trolox can quench free radicals and inhibit methylmercury (MeHg)-induced reactive oxygen species (ROS) generation in C6 glial cells. In addition, Trolox has demonstrated the ability to reduce cytotoxicity of Microcystis aeruginosa and microcystin-LR in Artemia franciscana nauplii.


Suppliers

Chemlyte Solutions
CS108324
Evonik ( formerly Wilshire Technologies, Inc. )
E2881152
CSNpharm, Inc.
CSN20793
Santa Cruz Biotechnology, Inc.
200810
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CAS equal suppliers

6-Hydroxy-2,5,7,8-tetramethylchroman-2-carboxylic Acid
TCI Chemicals (India) Pvt. Ltd.
H0726
6-Hydroxy-2,5,7,8-tetramethylchroman-2-carboxylic acid
Carbone Scientific Co., Ltd.
CS604818144
6-Hydroxy-2,5,7,8-tetramethylchroman-2-carboxylic acid
Hefei Hirisun Pharmatech Co., Ltd
HR012264
6-Hydroxy-2,5,7,8-tetramethylchroman-2-carboxylic Acid
Ascender Chemical Co.,Ltd
ACC540021600
6-Hydroxy-2,5,7,8-tetramethylchroman-2-carboxylic acid
AK Scientific, Inc.
AS410412312
6-Hydroxy-2,5,7,8-tetramethylchroman-2-carboxylic acid
Finetech Industry Limited
FIL540021600
6-Hydroxy-2,5,7,8-tetramethylchroman-2-carboxylic acid
Xingrui Industry Co., Limited
XIL626425056
6-Hydroxy-2,5,7,8-tetramethylchroman-2-carboxylic acid
XD BIOCHEMS Ltd
XB32409720
6-Hydroxy-2,5,7,8-tetramethylchroman-2-carboxylic acid
Xiamen Kinbester Co., Ltd.
XK561616848
6-Hydroxy-2,5,7,8-tetramethylchroman-2-carboxylic acid
Nantong Xindao Biotech Ltd
NXB561622464
6-Hydroxy-2,5,7,8-tetramethyl-chromane-2-carboxylic acid
Manchester Organics Limited
W52069
6-Hydroxy-2,5,7,8-tetramethylchroman-2-carboxylic acid (Trolox®,)
KJ Ross-Petersen ApS
KRA690027600

Prices & Availability




Data is processed


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Properties for Trolox

Molecular Weight:
250.29 g·mol−1
Density:
1.2 g/cm3 (Predicted)
Melting point:
187-189 °C(lit.)
Boiling point:
405.3-495.3° C at 760 mmHg (Predicted)
Solubility:
Soluble in 100% ethanol (25 mg/ml), methanol, water(slightly), DMSO (~20 mg/ml), DMF (~20 mg/ml), and PBS( pH7.2) (~3 mg/ml).
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Hazard Statements

GHS07

GHS03
Harmful
  • Acute toxicity (oral, dermal, inhalation), category 4
  • Skin irritation, categories 2, 3
  • Eye irritation, category 2A
  • Skin sensitization, category 1
  • Specific target organ toxicity following single exposure, category 3
    - Respiratory tract irritation
    - Narcotic effects
  • Not used
  • with the "skull and crossbones" pictogram
  • for skin or eye irritation if:
  • the "corrosion" pictogram also appears
  • the "health hazard" pictogram is used to indicate respiratory sensitization

Safety & Transport Information

Risk Codes:
R36/37/38 - Irritating to eyes, respiratory system and skin
Safety Codes:
S26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice
S36 - Wear suitable protective clothing
Hazard Symbols:
Xi
Hazard symbol Xi
Storage temperature :
0-6°C
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Alternative Distributors of [Trolox]

Producers or manufacturers change the product range from time to time. Currently there are no other manufacturers known.
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Downloads

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MSDS:
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