Trimidox | CAS 95933-74-7 | Chemical-Suppliers

Element: trimidox

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C-S » Chemicals » trimidox-PX78977

Identification

Trimidox

CAS:

95933-74-7

EINECS:

Molecular Formula:

C₇H₈N₂O₄

MDL:

MFCD02661510

SMILES:

C1=C(C(=O)C(=CC1=C(N)NO)O)O

Synonym:

trimidox exclusive ; vf 233 ; trimidox

Description

Trimidox is a specific ribonucleotide reductase inhibitor that reduces levels of dGTP and dCTP in HL-60 cells, inducing apoptosis via activation of caspases without altering the cell cycle distribution. Trimidox inhibits growth of human promyelocytic leukemia HL-6 cells with an IC₅₀ value of 35 µM.1

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Santa Cruz Biotechnology, Inc.

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Data is processed

Properties for Trimidox

Molecular Weight:

184.1494 g·mol−1

Density:

1.872 g/cm3

Melting point:

171.09° C (Predicted)

Boiling point:

249.7°C at 760 mmHg

Flash point:

104.8°C

Solubility:

Soluble in DMSO (~20 mg/ml), DMF (~20 mg/ml), and 1:2 solution of DMSO:PBS (pH 7.2) (~0.3 mg/ml).

Safety & Transport Information

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Alternative Distributors of [Trimidox]

Producers or manufacturers change the product range from time to time. Currently there are no other manufacturers known.

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Mol File:

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MSDS:

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