Trilostane | CAS 13647-35-3 | Chemical-Suppliers

Element: trilostane

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C-S » Chemicals » trilostane-PX78850

Identification

Trilostane

CAS:

13647-35-3

EINECS:

237-133-0

Molecular Formula:

C₂₀H₂₇NO₃

MDL:

MFCD00199295

SMILES:

C[C@]12CC[C@H]3[C@@H](CC[C@@]45O[C@@H]4C(O)=C(C[C@]35C)C#N)[C@@H]1CC[C@@H]2O

Synonym:

modrefen ; modrastane ; modrenal ; desopan ; vetoryl ; trilostane ,99% ; win 24540 ; 17-beta)-ph ; trilostane ; win-24540,desopan,modrastane,modrenal

Description

Trilostane is an inhibitor of isoforms 3β-HSD and 3β-HSD2 of the enzyme 3β-hydroxysteroid dehydrogenase, which plays a role in adrenal steroid biosynthesis. Investigators believe that Arg195 in 3∫-HSD versus Pro195 in 3β-HSD2 attributes to the competitive inhibition of 3β-HSD, but not 3β-HSD2 by Trilostane. Research shows that trilostane is effective in suppressing the intracellular production of androstenedione, testosterone, and dihydrotestosterone in LNCaP-FGC prostate cancer cells and inhibiting cortisol biosynthesis in the human adrenal gland. This product serves as a useful tool in steroid biosynthesis research.

Suppliers

Nantong Xindao Biotech Ltd

NXB2601040

Shanghai Chong Da Prostaglandin Fine Chemicals Co., Ltd.

SCDPFC5603920

Chemlyte Solutions

CS180540

Ambeed, Inc.

A378777

Conscientia Industrial Co., Ltd (Zhejiang Conscientia Pharmaceutical)

CI6902760

H&Z Industry Co.,Ltd

HIC200800

Autech Industry Co.,Limited

AIC2701080

Shandong SanYoung Industry Co., Ltd

SSI3501400

Guangzhou Topwork Chemical Co., Ltd.

GTC3601440

Hangzhou Cherry Pharmaceutical Technology Co., Ltd.

HCPT5102550

Shanghai Worldyang Chemical Co., Ltd.

SWC3701480

Sancai Industry Co.,Ltd.

SIC240960

Arakato Development Ltd

AD230690

Hangzhou Lingrui Chemical Co., Ltd.

HLC3501400

Finetech Industry Limited

FIL2501000

Carbone Scientific Co., Ltd.

CS280840

Pharmacore Co., Limited

PL230690

CM Fine Chemicals

CFC170680

AK Scientific, Inc.

AS190570

Xingrui Industry Co., Limited

XIL2901160

Capot Chemical Co., Ltd.

13638

BOC Sciences

BS120360

Leap Chem Co., Ltd

LC180540

Santa Cruz Biotechnology, Inc.

208469

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CAS equal suppliers

Androst-2-ene-2-carbonitrile, 4,5-epoxy-3,17-dihydroxy-, (4a,5a,17b)-

Angene International Limited

AGN-PC-0O1A42

(1S,2R,6R,8S,11S,12S,15S,16S)-5,15-dihydroxy-2,16-dimethyl-7-oxapentacyclo[9.7.0.0^{2,8}.0^{6,8}.0^{12,16}]octadec-4-ene-4-carbonitrile

Salsbury Chemicals, Inc.

SC48600145800

Prices & Availability

Data is processed

Properties for Trilostane

Molecular Weight:

329.43 g·mol−1

Melting point:

264 °C

Solubility:

DMSO, Pyridine

Safety & Transport Information

Risk Codes:

R36/37/38 - Irritating to eyes, respiratory system and skin
R62 - Possible risk of impaired fertility

Safety Codes:

S26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice
S36/37 - Wear suitable protective clothing and gloves

Hazard Symbols:

Storage temperature :

-20 °C Freezer

Alternative Distributors of [Trilostane]

Producers or manufacturers change the product range from time to time. The following companies
have appeared as suppliers in the past / currently not verified

Downloads

Mol File:

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MSDS:

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