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4-{4-[3-(4-Cl-3-trifluoromethyl-phenyl)-ureido]-phenoxy}-pyridine-2-carboxylic acid methylamide 4-methylbenzenesulfonate

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Formula: C21H16ClF3N4O3.C7H8SO3
CAS: 475207-59-1
search Element: methylbenzenesulfonate trifluoromethyl methylamide carboxylic pyridine phenoxy phenyl ureido acid
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Identification

Structural Formula
4-{4-[3-(4-Cl-3-trifluoromethyl-phenyl)-ureido]-phenoxy}-pyridine-2-carboxylic acid methylamide 4-methylbenzenesulfonate
CAS:
475207-59-1
EINECS:
Molecular Formula:
C21H16ClF3N4O3.C7H8SO3
MDL:
MFCD08235032
Synonym:
sorafenib impurity 1 ; sorafinib mesylate ; sorafenib & ; sorafenib tsoh salt ; sorafenib tosylate ; sorafenib & its intermediates ; sorafenib tosylate api ; sorafenib tosylate (nexavar) ; sorafenib (nexavar) ; sorafenib tosylate, >=99%




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CAS equal suppliers

Sorafenib
Hangzhou J&H Chemical Co., Ltd.
HJC2791116
Sorafenib tosylate
Molekula
64616082
Sorafenib Tosylate
Santa Cruz Biotechnology, Inc.
357801
Sorafenib tosylate
AK Scientific, Inc.
AS6842052
Sorafenib Tosylate
Hangzhou MolCore BioPharmatech Co.,Ltd.
MC20952
Sorafenib tosylate
Simagchem Corporation
SC7562268
Sorafenib tosylate
BOC Sciences
BS4321296
Sorafenib tosylate
Finetech Industry Limited
FIL9003600
Sorafenib tosylate
Chemieliva Pharmaceutical Co., Ltd.
CP12603780
Sorafenib tosylate
Leap Chem Co., Ltd
LC6481944
Sorafenib tosylate
Shanghai UCHEM Inc.
UCHEM-7021
Sorafenib Tosylate
Capot Chemical Co., Ltd.
22488
Sorafenib tosylate
LGM Pharma
LP3601080
Sorafenib tosylate
Medibro Corporation Limited
MCL9723888
Sorafenib tosylate
Haihang Industry Co., Ltd.
HI9362808
Sorafenib tosylate
Pharmacore Co., Limited
PL8282484
Sorafenib tosylate
Hangzhou Lingrui Chemical Co., Ltd.
HLC12605040
Sorafenib tosylate
Lonwin Industry Group Limited
LIGL10445220
Sorafenib Tosylate
Pharmaffiliates Analytics & Synthetics Pvt. Limited
PA 19 69000
Sorafenib tosylate
Dayang Chem (Hangzhou) Co.,Ltd.
DC11164464
Sorafenib tosylate
Autech Industry Co.,Limited
AIC9723888
Sorafenib tosylate
Hangzhou Yuhao Chemical Technology Co., Ltd
HL4112
Sorafenib tosylate
Ambeed, Inc.
A117299
Sorafenib Tosylate
Excenen Pharmatech Co., Ltd.
EN-4353
Sorafenib Tosylate
CSNpharm, Inc.
CSN12366
Sorafenib tosylate
Sancai Industry Co.,Ltd.
SIC8643456
Sorafenib tosylate
Aecochem Corp.
AC5041512
Sorafenib Tosylate
Aozeal Certified Standards (AOCS), Inc.
S0041.01
Sorafenib tosylate
FUDI Chemical Co. Ltd.
FCC7923168
Sorafenib tosylate
Conscientia Industrial Co., Ltd (Zhejiang Conscientia Pharmaceutical)
CI24849936
Sorafenib tosylate
Shandong Ench Chemical Co.,Ltd
SECC10805400
Sorafenib tosylate
Xingrui Industry Co., Limited
XIL10444176
Sorafenib tosylate
Zehao Industry Co., Ltd.
ZI8642592
Sorafenib tosylate
Gihi Chemicals Co., Limited
GCL9723888
Sorafenib tosylate
H&Z Industry Co.,Ltd
HIC7202880
Sorafenib tosylate
Hangzhou Cherry Pharmaceutical Technology Co., Ltd.
HCPT18369180
Sorafenib tosylate
Shandong SanYoung Industry Co., Ltd
SSI12605040
Sorafenib tosylate
Chemlyte Solutions
CS6481944
Sorafenib TsOH salt
Manchester Organics Limited
W96336
Sorafenibtosylate[USAN]
Huateng Pharmaceutical Co.,Ltd
80011517
4-[4-[[[[4-chloro-3-(trifluoroMethyl)phenyl]aMino]carbonyl]aMino]phenoxy]-N-Methyl-
Hefei Hirisun Pharmatech Co., Ltd
HR130335
4-(4-(3-(4-Chloro-3-(trifluoromethyl)phenyl)ureido)phenoxy)-N-methylpicolinamide 4-methylbenzenesulfonate
BLD Pharmatech Ltd
BP2079062370

Prices & Availability




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Properties for 4-{4-[3-(4-Cl-3-trifluoromethyl-phenyl)-ureido]-phenoxy}-pyridine-2-carboxylic acid methylamide 4-methylbenzenesulfonate

Molecular Weight:
637.03 g·mol−1
Melting point:
240-243 °C
Solubility:
Soluble in water (<1 mg/ml) at 25 °C, DMSO (127 mg/ml ) at 25 °C, and ethanol (<1 mg/ml ) at 25 °C.
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Hazard Statements

GHS07

GHS03
Harmful
  • Acute toxicity (oral, dermal, inhalation), category 4
  • Skin irritation, categories 2, 3
  • Eye irritation, category 2A
  • Skin sensitization, category 1
  • Specific target organ toxicity following single exposure, category 3
    - Respiratory tract irritation
    - Narcotic effects
    • Not used
  • with the "skull and crossbones" pictogram
  • for skin or eye irritation if:
  • the "corrosion" pictogram also appears
  • the "health hazard" pictogram is used to indicate respiratory sensitization

Safety & Transport Information

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Alternative Distributors of [4-{4-[3-(4-Cl-3-trifluoromethyl-phenyl)-ureido]-phenoxy}-pyridine-2-carboxylic acid methylamide 4-methylbenzenesulfonate]

Producers or manufacturers change the product range from time to time. The following companies
have appeared as suppliers in the past / currently not verified

YHEDC (Yi Heng Enterprises Development Co.) | CCS. CHEM. Co., Ltd. | ZhiYu Biotechnology Co., Ltd. | Taizhou Huading Chemical Co., Ltd. | Longschem Co., Ltd. | Melone Pharmaceutical Co., Ltd. | ShangHai Biochempartner Co., Ltd. | China Risesun Group Co., Ltd. | Shanghai Yongyi Biotechnology Co., Ltd. | Shanghai Yingxuan Chempharm Co., Ltd. | Shanghai AOKChem Group Limited | Kouting Chemical Co., Ltd. | Chemrio International Limited | TRUST&WE Co., Ltd. | Suzhou Vosun Chemical Co.,Ltd. | TCS INDUSTRY LTD. | Wuxi Mizat Chemical Technology Co., Ltd. | Nanjing CHICO Pharmaceutical Co., Ltd. | Evershine Chemical Co.,Ltd. | Anix-Chem Limited | Shanghai Marketing Center of Yangzhou Princechem Co., Ltd. | Hangzhou Pharma & Chem Co. Ltd. | Shanghai Boyle Chemical Co., Ltd. | Wuhan Sunrise Technology Development Company Ltd. | Jinan Great Chemical Co., Ltd. | ZhangJiaGang CAE International Trading Co., Ltd. | Hangzhou Imaginechem Co., Ltd. | Bichem Lab Co., Ltd. | China ShengDa Pharmaceutical Co., Ltd. | Zouping Mingxing Chemical Co., Ltd. | Shanghai Insight Chemicals Co., Ltd. | Hangzhou Holypharm Biotech Co., Ltd. | East Chemical Industry Co., Ltd. | Zhejiang Kaili Industrial Co., Ltd. | API Vanguard | Taizhou Creating Chemical Co., Ltd. | Shanghai Sunwise Chemical Co., Ltd. | All Right Chemical Co., Ltd. | Watson International Ltd | Pharmfar Co., Ltd. | Beijing Yangguang Furuide Chemical Co., Ltd. | Aopharm | BOC Sciences | Hubei Yuancheng Saichuang Tech.Co.,Ltd | Jinan Rouse Industry Co., Ltd. | Sciyu Biotech Co., Ltd. | Shijiazhuang Dingmin Pharmaceutical Sciences Co., Ltd. | Finetech Industry Limited | Jinan Haohua Industry Co., Ltd. | Beijing Mediking Biopharm Co., Ltd. | Trademax Phamaceuticals & Chemicals Co., Ltd. | Mengjiangnan Chemical Co., Ltd | Clearsynth Canada INC.

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