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20-trifluoro Leukotriene B4

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Formula: C20H29 F3 O4
CAS: 115178-97-7

Identification

Structural Formula
20-trifluoro Leukotriene B4
CAS:
115178-97-7
EINECS:
Molecular Formula:
C20H29 F3 O4
MDL:
SMILES:
C(CCC(F)(F)F)C/C=CC[C@H](/C=C/C=C/C=C[C@H](CCCC(=O)O)O)O
Synonym:
5s,12r-dihydroxy-20,20,20-trifluoro-6z,8e,10e,14z-eicosatetraenoic acid ; 20-trifluoromethyl-leukotriene b4 ; 20-trifluoromethyl leukotriene b4 ; (5s,6z,8e,10e,12r,14z)-20,20,20-trifluoro-5,12-dihydroxyicosa-6,8,10,14-tetraenoic acid ; 20-trifluoro leukotriene b4 ; 6,8,10,14-eicosatetraenoicacid, 20,20,20-trifluoro-5,12-dihydroxy-, (5s,6z,8e,10e,12r,14z)- ; 20,20,20-trifluoro-ltb4 ; 6,8,10,14-eicosatetraenoicacid, 20,20,20-trifluoro-5,12-dihydroxy-, [s-[r*,s*-(e,z,e,z)]]-


Description

20-trifluoro Leukotriene B4 (20CF3-LTB4) is a leukotriene B4 analog that contains equipotent chemoattractant capabilities and can resist ω-oxidation. Studies show that 20CF3-LTB4 can induce neutrophil desensitization to degranulation by leukotriene B4. 20CF3-LTB4 and other leukotrienes are reported to be potent eicosanoid lipid mediators derived from arachidonic acid. Most leukotrienes are involved in inflammatory responses and homeostatic biological functions. Further studies suggest that leukotrienes act via interaction with G protein-coupled receptors.


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Santa Cruz Biotechnology, Inc.
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Properties for 20-trifluoro Leukotriene B4

Molecular Weight:
390.44 g·mol−1
Density:
1.148 g/cm3
Boiling point:
530.5 °C at 760 mmHg
Flash point:
274.6 °C
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Alternative Distributors of [20-trifluoro Leukotriene B4]

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