trans-4-[(methylmaleimido)methyl]cyclohexane-1-carboxylic acid

Element: methylmaleimido cyclohexane carboxylic methyl trans acid

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C-S » Chemicals » trans-methylmaleimido-methyl-cyclohexane-carboxylic-acid-PX1826908

Identification

trans-4-[(methylmaleimido)methyl]cyclohexane-1-carboxylic acid

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Description

The introduction of a methyl group at the maleimido core improves the stability of maleimido-thiol conjugates. Reference: Development of novel linkers to conjugate pharmacophores to a carrier antibody; Moorthy S S Palanki , Abhijit Bhat , Rodney W Lappe, Bin Liu, Bryan Oates, John Rizzo; Bioorg.MedChem.Lett. 2012; 22(13): 4249-53. DOI: 10.1016/j.bmcl.2012.05.040

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