11-trans Leukotriene C4 | CAS 74841-69-3

Element: leukotriene trans

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C-S » Chemicals » trans-leukotriene-PX72031

Identification

11-trans Leukotriene C4

CAS:

74841-69-3

EINECS:

Molecular Formula:

C₃₀H₄₇N₃O₉S

MDL:

SMILES:

CCCCC/C=CC/C=C/C=C/C=C/C([C@H](CCCC(=O)O)O)SC[C@@H](C(=O)N(CC(=O)O)C(=O)CC[C@@H](C(=O)O)N)N

Synonym:

Description

11-trans Leukotriene C4 is a C-11 double bond isomer of LTC4, where LTC4 undergoes slow temperature-dependent isomerization to 11-trans LTC4 during storage. It has been produced in smaller amounts than LTC4 in human ionophore-stimulated HMC-1 cells and equine eosinophils, but not in RBL-1 cells and human neutrophils. It is nearly equipotent with LTC4 for contraction of guinea pig ileum and parenchyma.