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trans Lacidipine

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Formula: C26H33NO6
CAS: 103890-78-4
search Element: lacidipine trans

Identification

Structural Formula
trans Lacidipine
CAS:
103890-78-4
EINECS:
Molecular Formula:
C26H33NO6
MDL:
MFCD00865936
SMILES:
CCOC(=O)C1=C(NC(=C(C1C2=CC=CC=C2C=CC(=O)OC(C)(C)C)C(=O)OCC)C)C
Synonym:
gx-1048 ; lacirex ; cid 5311217 ; lacipil ; motens ; lacidipin ; caldine ; lacidipine ; sn-305 ; gr-43659x


Description

trans Lacidipine is a dihydropyridine calcium channel protein inhibitor and blocker. Structurally, trans Lacidipine is characterized by its cinnamate moiety, which results in specific photochemical properties that differ from other dihydropyridine. Studies indicate that upon irradtiation with monochromatic radiation at λ=313 nm, cis Lacidipine was degraded and the concentration of trans Lacidipine was increased. It is known that calcium channel blockers such as trans Lacidipine function by blocking voltage gated calcium channels on cell membranes of cardiac muscle and blood vessels. As a result of this inhibition there is a reduction in cardiac muscle and blood vessel contraction.


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Prices & Availability




Data is processed


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Properties for trans Lacidipine

Molecular Weight:
455.54 g·mol−1
Melting point:
174-175 °C
Solubility:
Soluble in Chloroform
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Hazard Statements

GHS07

GHS03
Harmful
  • Acute toxicity (oral, dermal, inhalation), category 4
  • Skin irritation, categories 2, 3
  • Eye irritation, category 2A
  • Skin sensitization, category 1
  • Specific target organ toxicity following single exposure, category 3
    - Respiratory tract irritation
    - Narcotic effects
  • Not used
  • with the "skull and crossbones" pictogram
  • for skin or eye irritation if:
  • the "corrosion" pictogram also appears
  • the "health hazard" pictogram is used to indicate respiratory sensitization

Safety & Transport Information

Risk Codes:
R22 - Harmful if swallowed
Hazard Symbols:
Xn
Hazard symbol Xn
Storage temperature :
-20°C Freezer
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Alternative Distributors of [trans Lacidipine]

Producers or manufacturers change the product range from time to time. Currently there are no other manufacturers known.
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Downloads

Mol File:
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MSDS:
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