Topiramate | CAS 97240-79-4 | Chemical-Suppliers

Element: topiramate

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C-S » Chemicals » topiramate-PX64531

Identification

Topiramate

CAS:

97240-79-4

EINECS:

Molecular Formula:

C₁₂H₂₁NO₈S

MDL:

MFCD00865320

SMILES:

CC1(OC2COC3(C(C2O1)OC(O3)(C)C)COS(=O)(=O)N)C

Synonym:

topomax ; topiramate ; topimax ; topamac ; mcn 4853 ; epitoma ; topamax ; topina ; rwj 17021 ; epitomax

Description

Topiramate is an anticonvulsant that antagonizes GluR5 receptors (IC₅₀ = 0.46 μM) and acts as a positive allosteric modulator of GABA_A receptor-mediated currents. This compound inhibits Nav channels (IC₅₀ = 48.9 μM) and inhibits L-type Ca²⁺ channels. Topiramate inhibits carbonic anhydrase (CA) (K_i values are 0.1 and 0.2 μM in rat CA II and CA IV, respectively).

Suppliers

Aozeal Certified Standards (AOCS), Inc.

T0005.00

Conscientia Industrial Co., Ltd (Zhejiang Conscientia Pharmaceutical)

CI6902760

H&Z Industry Co.,Ltd

HIC200800

Autech Industry Co.,Limited

AIC2701080

Shandong SanYoung Industry Co., Ltd

SSI3501400

Nantong Xindao Biotech Ltd

NXB2601040

Chemlyte Solutions

CS180540

CellMark AB

CA110330

IBIS Chemie International

ICI2501000

X´ian Taicheng Chem Co., Ltd

XTC2901160

Xiamen Equation Chemical Co.,Ltd

XECC3201600

Sancai Industry Co.,Ltd.

SIC240960

Arakato Development Ltd

AD230690

Aecochem Corp.

AC140420

CSNpharm, Inc.

CSN12115

Hangzhou Keying Chem Co., Ltd.

HKC3001200

Finetech Industry Limited

FIL2501000

Carbone Scientific Co., Ltd.

CS280840

AK Scientific, Inc.

AS190570

Xingrui Industry Co., Limited

XIL2901160

Leap Chem Co., Ltd

LC180540

Santa Cruz Biotechnology, Inc.

204350

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CAS equal suppliers

TOPIRAMATE - USP/IP

Corey Organics PVT Limited

COPL19769880

Prices & Availability

Data is processed

Properties for Topiramate

Molecular Weight:

339.36 g·mol−1

Density:

~1.3 g/cm³ (Predicted)

Melting point:

125 °C

Boiling point:

~438.7° C at 760 mmHg (Predicted)

Solubility:

DMSO: ~44 mg/mL

Safety & Transport Information

Risk Codes:

R11 - Highly flammable
R23/24/25 - Toxic by inhalation, in contact with skin and if swallowed
R36/37/38 - Irritating to eyes, respiratory system and skin
R39/23/24/25 - Toxic: danger of very serious irreversible effects through inhalation, in contact with skin and if swallowed

Safety Codes:

S16 - Keep away from sources of ignition - No smoking
S26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice
S36 - Wear suitable protective clothing
S36/37 - Wear suitable protective clothing and gloves
S45 - In case of accident or if you feel unwell seek medical advice immediately (show the label where possible)
S7 - Keep container tightly closed

Hazard Symbols:

Xi, T, F

Storage temperature :

2-8°C

Alternative Distributors of [Topiramate]

Producers or manufacturers change the product range from time to time. The following companies
have appeared as suppliers in the past / currently not verified