TMPyP4, tetra-(N-methyl-4-pyridyl)porphyrin, is a potent inhibitor of human TERT (telomerase, IC50 = 6.5 μM). TMPyP4 binds strongly to DNA quadruplexes by stacking on the G-tetrads at the core of the quadruplex, resulting in telomerase inhibition. TMPyP4 fluoresces intensely in the presence of quadruplex DNA.
TMPyP [=alpha,beta,gamma,delta-Tetrakis(1-methylpyridinium-4-yl)porphyrin p-Toluenesulfonate] [Ultra-high sensitive spectrophotometric reagent for Cu, Mg] [For the simultaneous determination of metals
TCI Chemicals (India) Pvt. Ltd.
A5014
Prices & Availability
Data is processed
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Properties for TMPyP4
Molecular Weight:
1363.6 g·mol−1
Solubility:
Soluble in water (1 mg/ml).
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Safety & Transport Information
Risk Codes:
R36/37/38 - Irritating to eyes, respiratory system and skin
Safety Codes:
S26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice S36/37 - Wear suitable protective clothing and gloves
Hazard Symbols:
Xi
Storage temperature :
2-8°C
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Alternative Distributors of [TMPyP4]
Producers or manufacturers change the product range from time to time. Currently there are no other manufacturers known.