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Ticrynafen

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Formula: C13H8Cl2O4S
CAS: 40180-04-9
search Element: ticrynafen

Identification

Structural Formula
Ticrynafen
CAS:
40180-04-9
EINECS:
Molecular Formula:
C13H8Cl2O4S
MDL:
MFCD00867339
SMILES:
C1=CSC(=C1)C(=O)C2=C(C(=C(C=C2)OCC(=O)O)Cl)Cl
Synonym:
ce3624 ; diflurex ; skf62698 ; anp3624 ; tienilic ; tienilic acid ; ticrex ; selacryn ; difluorex ; tienilicacid ; fr3068


Description

Ticrynafen is a heterocyclic derivative of phenoxyacetic acid which inhibits cytochrome P450 (CYP). Ticrynafen is also a substrate of CYP2C9


Suppliers

Santa Cruz Biotechnology, Inc.
220253
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CAS equal suppliers

Tienilic acid
Salsbury Chemicals, Inc.
SC6241872
2,3-Dichloro-4-(2-thenoyl)phenoxyacetic acid
Leap Chem Co., Ltd
LC396011880
2,3-Dichloro-4-(2-thenoyl)phenoxyacetic acid
Finipharma Ltd
F30806160
Acetic acid, [2,3-dichloro-4-(2-thienylcarbonyl)phenoxy]-
Angene International Limited
AGN-PC-0JKQ91

Prices & Availability




Data is processed


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Properties for Ticrynafen

Molecular Weight:
331.17 g·mol−1
Density:
1.532
Melting point:
148-149°C
Boiling point:
534.57° C at 760 mmHg (Predicted)
Solubility:
Soluble in DMSO (~30 mg/ml), ethanol (~30 mg/ml), methanol (~1 mg/ml), and DMF (~30 mg/ml). Insoluble in water at 25 ºC.
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Hazard Statements

GHS07

GHS03
Harmful
  • Acute toxicity (oral, dermal, inhalation), category 4
  • Skin irritation, categories 2, 3
  • Eye irritation, category 2A
  • Skin sensitization, category 1
  • Specific target organ toxicity following single exposure, category 3
    - Respiratory tract irritation
    - Narcotic effects
  • Not used
  • with the "skull and crossbones" pictogram
  • for skin or eye irritation if:
  • the "corrosion" pictogram also appears
  • the "health hazard" pictogram is used to indicate respiratory sensitization

Safety & Transport Information

Poison by intravenous route. Moderately toxic by ingestion. Human systemic effects by ingestion: nausea or vomiting, kidney damage and decreased urine volume or anuria. Mutation data reported. Used as a diuretic, uricosuric and antihypertensive. When heated to decomposition it emits toxic fumes of Cl− and SOx.
Risk Codes:
R22 - Harmful if swallowed
Hazard Symbols:
Xn
Hazard symbol Xn
Storage temperature :
-20 °C Freezer
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Alternative Distributors of [Ticrynafen]

Producers or manufacturers change the product range from time to time. The following companies
have appeared as suppliers in the past / currently not verified

BOC Sciences | Suzhou Vosun Chemical Co.,Ltd. | Jinjiangchem Corporation | Wanko Chemical Co., Ltd.

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Downloads

Mol File:
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MSDS:
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