DL-threo-PDMP, Hydrochloride
Formula: C23H38 N2 O3 . Cl H
CAS: 80938-69-8
Identification
DL-threo-PDMP, Hydrochloride
Molecular Formula:
C2 3 H3 8 N2 O3 . Cl H
SMILES:
CCCCCCCCCC(N([H])[C@H]([C@@H](O)C1=CC=CC=C1)CN2CCOCC2)=O.Cl
Synonym:
dl-pdmp ; 1-phenyl-2-decanoylamino-3-morpholino-1-propanol, hcl ; (±)-threo-pdmp hydrochloride, pdmp hydrochloride ; dl-threo-pdmp, hydrochloride ; decanamide,n-[(1r,2r)-2-hydroxy-1-(4-morpholinylmethyl)-2-phenylethyl]-, hydrochloride(1:1), rel- ; pdmp ; (+)-threo-1-phenyl-2-decanoylamino-3-*morpholino- ; (+)-threo-1-phenyl-2-decanoylamino-3-*mo rpholino-1- ; decanamide,n-[2-hydroxy-1-(4-morpholinylmethyl)-2-phenylethyl]-, monohydrochloride,(r*,r*)- (9ci) ; decanamide,n-[2-hydroxy-1-(4-morpholinylmethyl)-2-phenylethyl]-, monohydrochloride,(r*,r*)-(?à )- ; pdmp hydrochloride \ glucosylceramide sy nthase inhibitor ; (+/-)-threo-pdmp hydrochloride ; d,l-threo-pdmp hcl
Description
DL-threo-PDMP, Hydrochloride is a PDMP which closely resembles the natural sphingolipid substrate of brain glucosyltransferase and acts as a potent and competitive inhibitor of this enzyme. Blocks the outgrowth of neurites and inhibits glycolipid synthesis in cultured NIH/3T3 cells. DL-threo-PDMP, Hydrochloride is an inhibitor of UGCG (Glucosylceramide synthase).
Suppliers
Santa Cruz Biotechnology, Inc.
203030
Prices & Availability
Data is processed
Properties
Safety & Transport
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Properties for DL-threo-PDMP, Hydrochloride
Molecular Weight:
427.02 g·mol−1
Melting point:
157-162° C
Solubility:
Soluble in ethanol (50 mg/ml), water (0.05 mg/ml) at 25° C, DMSO (30 mg/ml), DMF (25 mg/ml), and 1:5 ethanol:PBS(pH 7.2) (~0.05 mg/ml).
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Safety & Transport Information
Risk Codes:
R36/37/38 - Irritating to eyes, respiratory system and skin
Safety Codes:
S26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice
Hazard Symbols:
Xi
Storage temperature :
-20°C
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Alternative Distributors of [DL-threo-PDMP, Hydrochloride]
Producers or manufacturers change the product range from time to time.
Currently there are no other manufacturers known.
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