Thioetheramide PC | CAS 116457-99-9

Element: thioetheramide

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C-S » Chemicals » thioetheramide-PX63530

Identification

Thioetheramide PC

CAS:

116457-99-9

EINECS:

Molecular Formula:

C₄₀H₈₃ N₂ O₅ P S

MDL:

SMILES:

CCCCCCCCCCCCCCCCSC[C@H](COP(=O)(O)OCC[N](C)(C)C)NC(=O)CCCCCCCCCCCCCCC

Synonym:

3,5-dioxa-9-thia-4-phosphapentacosan-1-aminium,4-hydroxy-n,n,n-trimethyl-7-[(1-oxohexadecyl)amino]-, inner salt, 4-oxide,(7s)- ; thioetheramide pc ; 1,2-dideoxy-1-(s-hexadecyl)thio-2-(n-hexadecanoyl)amino-sn-glyceryl-3-phosphorylcholine ; 1-palmitylthio-2-palmitoylamido-1,2-dideoxy-sn-glycero-3-phosphorylcholine ; 3,5-dioxa-9-thia-4-phosphapentacosan-1-aminium,4-hydroxy-n,n,n-trimethyl-7-[(1-oxohexadecyl)amino]-, inner salt, 4-oxide, (s)- ; thioetheramide phosphorylcholine ; 1-palmitylthio-2-palmitoylamino-1,2-dideoxy-sn-glycero-3-phosphorylcholine ; 1-palmitylthio-2-palmitoylamido-1,2-dideoxy-sn-glycero-3-phosphocholine

Description

Thioetheramide-PC is a reversible inhibitor of secretory phospholipase A2 (sPLA2) that binds to both the catalytic site and activator site of sPLA2. The PLA2 enzyme is found Chinese cobra snake venom and it binds more firmly to the activator site of the enzyme in comparison to the catalytic site. Research indicates that Thioetheramide-PCs ability to bind to both sites may be due to the phophoslipase activation that occurs with low concentrations of the compound, which does not inhibit the enzyme.

Suppliers

Santa Cruz Biotechnology, Inc.

202840

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Prices & Availability

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Properties for Thioetheramide PC

Molecular Weight:

789.27 g·mol−1

Melting point:

115-120

Solubility:

DMSO, 100% ethanol or methanol.

Safety & Transport Information

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Alternative Distributors of [Thioetheramide PC]

Producers or manufacturers change the product range from time to time. Currently there are no other manufacturers known.

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Mol File:

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MSDS:

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