L-thiocitrulline, Dihydrochloride | CAS 212051-53-1

Element: dihydrochloride thiocitrulline

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Identification

L-thiocitrulline, Dihydrochloride

CAS:

212051-53-1

EINECS:

Molecular Formula:

C₆H₁₃ N₃ O₂ S . 2 Cl H

MDL:

MFCD00935993

SMILES:

C(C[C@@H](C(=O)O)N)CNC(=S)N.Cl.Cl

Synonym:

2-THIOUREIDO-L-NORVALINE ; 2-THIOUREIDO-L-NORVALINE, DIHYDROCHLORIDE ; L-THIOCITRULLINE DIHYDROCHLORIDE ; N5-(AMINOTHIOXOMETHYL)-L-ORNITHINE, DIHYDROCHLORIDE ; L-TC dihydrochloride ; L-Ornithine,N5-(aminothioxomethyl)-, dihydrochloride (9CI)

Description

L-thiocitrulline, Dihydrochloride is a potent stereospecific inhibitor of all three isoforms of rat NOS (NOS1, NOS2, and NOS3) that has greater inhibitory activity on NOS1 (nNOS) (Ki = 60 nM) compared to NOS2 (iNOS) (Ki = 3.6 μM). L-thiocitrulline inhibition is competitive with respect to L-Arginine, a native substrate, which suggests that L-thiocitrulline preferentially occupies the L-Arginine binding site.

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L-Thiocitrulline dihydrochloride

Santa Cruz Biotechnology, Inc.

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(2S)-2-Amino-5-(carbamothioylamino)pentanoic acid dihydrochloride

Chemlyte Solutions

CS936028080

Prices & Availability

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Properties for L-thiocitrulline, Dihydrochloride

Molecular Weight:

264.17 g·mol−1

Density:

1.33 g/cm3

Melting point:

55-65 °C

Boiling point:

399.8°C at 760 mmHg

Flash point:

195.6°C

Safety & Transport Information

Safety Codes:

S24/25 - Avoid contact with skin and eyes

Alternative Distributors of [L-thiocitrulline, Dihydrochloride]

Producers or manufacturers change the product range from time to time. Currently there are no other manufacturers known.

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