2-thio PAF | CAS 96801-55-7 | Chemical-Suppliers

Element: thio

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C-S » Chemicals » thio-paf-PX78454

Identification

2-thio PAF

CAS:

96801-55-7

EINECS:

Molecular Formula:

C₂₆H₅₄ N O₆ P S

MDL:

SMILES:

CCCCCCCCCCCCCCCCOCC(COP(=O)(O)OCC[N+](C)(C)C)SC(=O)C

Synonym:

3,5,9-trioxa-4-phosphapentacosan-1-aminium,7-(acetylthio)-4-hydroxy-n,n,n-trimethyl-, inner salt, 4-oxide, (7r)- ; 1-o-hexadecyl-2-deoxy-2-thio-s-acetyl-sn-glyceryl-3-phosphorylcholine ; 3,5,9-trioxa-4-phosphapentacosan-1-aminium,7-(acetylthio)-4-hydroxy-n,n,n-trimethyl-, inner salt, 4-oxide, (r)- ; 2-thio paf

Description

2-thio PAF is an isosteric analog of PAF, while it is also a synthetic analog which contains an acetyl group attached by a thioester bond at the sn-2 position. 2-thio PAF functions as a PAF receptor agonist, and its potency is comparable to PAF C-18 in rabbit platelet aggregation, and to PAF C-16 in the activation of guinea pig macrophages.1 2-thio PAF is a substrate for lysophospholipase II and for PAF-AH.2