Tetrabenazine | CAS 58-46-8 | Chemical-Suppliers

Element: tetrabenazine

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C-S » Chemicals » tetrabenazine-PX70508

Identification

Tetrabenazine

CAS:

58-46-8

EINECS:

200-383-6

Molecular Formula:

C₁₉H₂₇ N O₃

MDL:

MFCD08461052

SMILES:

CC(C)CC1CN2CCC3=CC(=C(C=C3C2CC1=O)OC)OC

Synonym:

rubigen ; 2h-benzo[a]quinolizin-2-one,1,3,4,6,7,11b-hexahydro-3-isobutyl-9,10-dimethoxy- (6ci,8ci) ; ro 1-9569 ; nsc 169886 ; 3-isobutyl-9,10-dimethoxy-3,4,6,7-tetrahydro-1h-pyrido[2,1-a]isoquinolin-2(11bh) ; tetrabenazine ; 9,10-dimethoxy-1,3,4,6,7,11b-hexahydro-3-isobutyl-2h-benzo[a]quinolizin-2-one ; (3r,11br)-rel- ; 3-isobutyl-9,10-dimethoxy-1,3,4,6,7,11b-hexahydropyrido[2,1-a]isoquinolin-2-one ; cis-9,10-dimethoxy-1,3,4,6,7,11b-hexahydro-3-isobutyl-2h-benzo[a]quinolizin-2-one ; (?Ã )-tetrabenazine ; cis-2-oxo-3-isobutyl-9,10-dimethoxy-1,2,3,4,6,7-hexahydro-11bh-benzo[a]quinolizine ; nitoman ; nsc172187 ; 2h-benzo[a]quinolizin-2-one,1,3,4,6,7,11b-hexahydro-9,10-dimethoxy-3-(2-methylpropyl)-, cis- ; 3-isobutyl-9,10-dimethoxy-1,3,4,6,7,11b-hexahydro-2h-benzo[a]quinolizin-2-one ; 2h-benzo[a]quinolizin-2-one,1,3,4,6,7,11b-hexahydro-9,10-dimethoxy-3-(2-methylpropyl)-, (3r,11br)-rel-

Description

Tetrabenazine is a potent inhibitor of vesicular monoamine uptake; depletes stores of serotonin, dopamine and noradrenalin. Binds with high affinity (IC₅₀ = 3.2 nM) to vesicular monoamine transporter (VMAT) in chromaffin granule membranes and displays higher affinity for VMAT2 than VMAT1. Also reported to block dopamine receptors.

Suppliers

Aozeal Certified Standards (AOCS), Inc.

T0024.00

Conscientia Industrial Co., Ltd (Zhejiang Conscientia Pharmaceutical)

CI8973588

Aea.ltd

A91182

Inke S.A.

IS117351

Hangzhou Keying Chem Co., Ltd.

HKC3901560

Wanko Chemical Co., Ltd.

WC312936

Finetech Industry Limited

FIL3251300

Carbone Scientific Co., Ltd.

CS3641092

Xingrui Industry Co., Limited

XIL3771508

Capot Chemical Co., Ltd.

26005

BOC Sciences

BS156468

Leap Chem Co., Ltd

LC234702

Santa Cruz Biotechnology, Inc.

204338

Dayang Chem (Hangzhou) Co.,Ltd.

DC4031612

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CAS equal suppliers

Tizanidine

Aozeal Certified Standards (AOCS), Inc.

T0032.00

Tetrabenazine Labeled d7

Santa Cruz Biotechnology, Inc.

sc-356121

Prices & Availability

Data is processed

Properties for Tetrabenazine

Molecular Weight:

317.47 g·mol−1

Density:

1.12

Melting point:

128-130 °C C

Boiling point:

448.9°C at 760 mmHg

Flash point:

225.3°C

Solubility:

Soluble in ethanol (30 mM), DMSO (100 mM), water (hot), alcohol, and chloroform.

Safety & Transport Information

Poison by subcutaneous and intraperitoneal routes. Moderately toxic by ingestion. Experimental reproductive effects. When heated to decomposition it emits toxic fumes of NOx.

Risk Codes:

Hazard Classes:

6.1(b)

Hazard Symbols:

Storage temperature :

2-8°C

RID/ADR certification :

3249

Alternative Distributors of [Tetrabenazine]

Producers or manufacturers change the product range from time to time. The following companies
have appeared as suppliers in the past / currently not verified