Sulfasalazine | CAS 599-79-1 | Chemical-Suppliers

Element: sulfasalazine

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C-S » Chemicals » sulfasalazine-PX68078

Identification

Sulfasalazine

CAS:

599-79-1

EINECS:

209-974-3

Molecular Formula:

C₁₈H₁₄N₄O₅S

MDL:

MFCD00057363

SMILES:

C1=CC=NC(=C1)NS(=O)(=O)C2=CC=C(C=C2)NN=C3C=CC(=O)C(=C3)C(=O)O

Synonym:

azopyrin ; rorasul ; sas-500 ; ssz ; sulcolon ; reupirin ; accucol ; salisulf ; sasp ; si-88

Description

Sulfasalazine is an antiinflammatory agent that inhibits GSH-H-transferase. Sulfasalazine largely inhibits NF-κB activation and induces apoptosis in T-lymphocytes. The compound also engages neutrophil apoptosis that can be abrogated by Tyr-K inhibitors, PKA inhibitors, or antioxidants. Sulfasalazine is shown to inhibit basic fibroblast growth factor-induced endothelial cell chemotaxis. Sulfasalazine is an inhibitor of TNFα and an activator of PPARγ.

Suppliers

Ambeed, Inc.

A176325

Aozeal Certified Standards (AOCS), Inc.

S0008.00

Conscientia Industrial Co., Ltd (Zhejiang Conscientia Pharmaceutical)

CI8973588

Lori Industry Co., Ltd

LI286858

H&Z Industry Co.,Ltd

HIC2601040

Refine Chemical Co.,Ltd.

RCC3121248

Nantong Xindao Biotech Ltd

NXB3381352

Create Chemical Co., Ltd.

CC325975

XD BIOCHEMS Ltd

XB195585

Autech Industry Co.,Limited

AIC3511404

Tessenderlo Chemie

TC234702

X´ian Taicheng Chem Co., Ltd

XTC3771508

Sancai Industry Co.,Ltd.

SIC3121248

Arakato Development Ltd

AD299897

Hainan Zhongxin Chemical Co., Ltd.

HZC4421768

CSNpharm, Inc.

CSN12011

Hangzhou Lingrui Chemical Co., Ltd.

HLC4551820

Sigma-Aldrich International GmbH

SI4161248

Carbone Scientific Co., Ltd.

CS3641092

AK Scientific, Inc.

AS247741

Simagchem Corporation

SC273819

Xingrui Industry Co., Limited

XIL3771508

Santa Cruz Biotechnology, Inc.

204312

Chemos GmbH & Co. KG

CC260780

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Prices & Availability

Data is processed

Properties for Sulfasalazine

Molecular Weight:

398.4 g·mol−1

Density:

1.50 g/cm³ at 25° C

Melting point:

260-265 °C (dec.)(lit.)

Boiling point:

689.35° C at 760 mmHg (Predicted)

Solubility:

NH₄OH 1 M: 50 mg/mL, clear, red

Hazard Statements

GHS08
Health hazard

Respiratory sensitization, category 1
Germ cell mutagenicity, categories 1A, 1B, 2
Carcinogenicity, categories 1A, 1B, 2
Reproductive toxicity, categories 1A, 1B, 2
Specific target organ toxicity following single exposure, categories 1, 2
Specific target organ toxicity following repeated exposure, categories 1, 2
Aspiration hazard, categories 1, 2

Safety & Transport Information

Risk Codes:

R42/43 - May cause sensitization by inhalation and skin contact

Safety Codes:

S22 - Do not breathe dust
S29/56 - Do not empty into drains, dispose of this material and its container at hazardous or special waste collection point
S45 - In case of accident or if you feel unwell seek medical advice immediately (show the label where possible)

Hazard Symbols:

Storage temperature :

Refrigerator

Alternative Distributors of [Sulfasalazine]

Producers or manufacturers change the product range from time to time. The following companies
have appeared as suppliers in the past / currently not verified