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Suberoylanilide Hydroxamic Acid

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Formula: C14H20N2O3
CAS: 149647-78-9

Identification

Structural Formula
Suberoylanilide Hydroxamic Acid
CAS:
149647-78-9
EINECS:
Molecular Formula:
C14H20N2O3
MDL:
MFCD00945317
SMILES:
C1=CC=C(C=C1)NC(=O)CCCCCCC(=O)NO
Synonym:
unii-58ifb293ji ; saha cpd ; vorinostat ; vorinostat impurity ; saha, >=99% ; vorinostat/saha ; vorinostat-13c6 ; vorinastat ; mk0683 ; ccris 8456


Description

Suberoylanilide Hydroxamic Acid (SAHA) is a potent histone deacetylase (HDAC) inhibitor that has been shown to inhibit proliferation and cause cell cycle arrest at G1. Experiments suggest that SAHA also causes morphological changes, such as enlargement and flattening of the cytoplasm, resulting in growth inhibition. Treatment of cells with SAHA also decreases the expression of anti-apoptosis proteins Bcl-xL and survivin.


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Prices & Availability




Data is processed


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Properties for Suberoylanilide Hydroxamic Acid

Molecular Weight:
264.32 g·mol−1
Density:
~1.2 g/cm3 (Predicted)
Melting point:
161-162 °C
Solubility:
Soluble in ethanol (3 mg/ml at 25° C), DMSO (53 mg/ml at 25° C), DMF (~20 mg/ml), water (1.17 mg/ml at 25° C), and methanol.
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Safety & Transport Information

Risk Codes:
R61 - May cause harm to the unborn child
R68 - Possible risk of irreversible effects
Safety Codes:
S36/37 - Wear suitable protective clothing and gloves
S45 - In case of accident or if you feel unwell seek medical advice immediately (show the label where possible)
S53 - Avoid exposure - obtain special instructions before use
Hazard Symbols:
T
Hazard symbol T
Storage temperature :
-20 °C Freezer
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Alternative Distributors of [Suberoylanilide Hydroxamic Acid]

Producers or manufacturers change the product range from time to time. The following companies
have appeared as suppliers in the past / currently not verified

Jinan Haohua Industry Co., Ltd. | Zhengzhou Versailles-Special Chemical Technology Co., Ltd.

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