Identification
Stem-Cell Factor/c-Kit Inhibitor, ISCK03
Molecular Formula:
C1 9 H2 1 N3 O2 S
SMILES:
CC(C)(C)C1=CC=C(C=C1)S(=O)(=O)NC2=CC=C(C=C2)N3C=CN=C3
Synonym:
benzenesulfonamide,4-(1,1-dimethylethyl)-n-[4-(1h-imidazol-1-yl)phenyl] ; isck03 ; stem-cell factor/c-kit inhibitor, isck03 ; [4-t-butylphenyl]-n-(4-imidazol-1-yl phenyl)sulfonamide, benzenesulfonamide, 4-(1,1-dimethylethyl)-n-[4-(1h-imidazol-1-yl)phenyl]- ; [4-t-butylphenyl]-n-(4-imidazol-1-yl phenyl)sulfonamide
Description
Stem-Cell Factor/c-Kit Inhibitor, ISCK03 is a cell-permeable phenyl-imidazolosulfonamide compound that inhibits c-kit activity (IC50 <<2.5 μM in cell-free kinase assays) and blocks SCF-induced c-kit and Erk phosphorylation (1 μM causes >90% inhibition) without any effect on HGF-induced Erk phosphorylation in 501mel melanoma cells.
Suppliers
Santa Cruz Biotechnology, Inc.
355981
CAS equal suppliers
ISCK03
ShangHai Biochempartner Co., Ltd.
BCP20053
ISCK03
Ambeed, Inc.
A263965
ISCK03
Excenen Pharmatech Co., Ltd.
EX-A1323
ISCK03
CSNpharm, Inc.
CSN20497
ISCK03
Amadis Chemical Company Limited
ACCL186930
Prices & Availability
Data is processed
Properties
Safety & Transport
Alternative Distributors
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Properties for Stem-Cell Factor/c-Kit Inhibitor, ISCK03
Molecular Weight:
355.46 g·mol−1
Density:
1.2 g/cm3 (Predicted)
Melting point:
230.08 °C (Predicted)
Boiling point:
519.99 °C at 760 mmHg (Predicted)
Solubility:
Soluble in DMSO (10 mg/ml), and ethanol (5 mg/ml). Insoluble in water.
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Safety & Transport Information
Risk Codes:
R36 - Irritating to eyes
Safety Codes:
S26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice
Hazard Symbols:
Xi
Storage temperature :
2-8°C
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Alternative Distributors of [Stem-Cell Factor/c-Kit Inhibitor, ISCK03]
Producers or manufacturers change the product range from time to time.
Currently there are no other manufacturers known.
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