1-Stearoyl-2-Arachidonoyl PC | CAS 35418-59-8

Element: arachidonoyl stearoyl

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Identification

1-Stearoyl-2-Arachidonoyl PC

CAS:

35418-59-8

EINECS:

Molecular Formula:

C₄₆H₈₄ N O₈ P

MDL:

MFCD00082436

SMILES:

CCCCCCCCCCCCCCCCCC(=O)OC[C@H](COP(=O)([O-])OCC[N+](C)(C)C)OC(=O)CCC/C=CC/C=CC/C=CC/C=CCCCCC

Synonym:

1-stearoyl-2-arachidonoyl-sn-glycero-3-phosphocholine ; 3,5,8-trioxa-4-phosphaoctacosa-13,16,19,22-tetraen-1-aminium,4-hydroxy-n,n,n-trimethyl-9-oxo-7-[[(1-oxooctadecyl)oxy]methyl]-, inner salt,4-oxide, (7r,13z,16z,19z,22z)- ; l-β-arachidonoyl-γ-stearoyl-α-lecithin ; 1-stearoyl-2-arachidonoylphosphatidylcholine ; 1-octadecanoyl-2-arachidonyl-sn-glycero-3-phosphocholine ; sapc ; l-beta-arachidonoyl-gamma-stearoyl-alpha-lecithin ; 1-stearoyl-2-archidonyl-3-sn-phosphatidylcholine ; l-α-phosphatidylcholine, β-arachidonoyl-γ-stearoyl ; 3-sn-phosphatidylcholine, 2-arachidonoyl-1-stearoyl ; 3,5,8-trioxa-4-phosphaoctacosa-13,16,19,22-tetraen-1-aminium,4-hydroxy-n,n,n-trimethyl-9-oxo-7-[[(1-oxooctadecyl)oxy]methyl]-, inner salt,4-oxide, [r-(all-z)]- ; 1-stearoyl-2-arachidonoyl pc ; 1-stearoyl-2-arachidonoyl-sn-glycero-3-phosphorylcholine ; 18:0/20:4 phosphatidylcholine ; 18:0-20:4 pc

Description

1-Stearoyl-2-arachidonoyl phosphatidylcholine (SAPC) is an important source of activation-induced arachidonate released as a substrate for cyclooxygenase (COX-2) mediated signaling. It is the preferred substrate for the 85 kDa cytosolic phospholipase, which translocates to endoplasmic and nuclear membranes in response to the activation-induced rise in intracellular calcium. The arachidonate thus liberated can be utilized by either COX or lipoxygenase enzymes for the elaboration of further eicosanoid mediators.

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Santa Cruz Biotechnology, Inc.

204954

Dayang Chem (Hangzhou) Co.,Ltd.

DC260410416

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Data is processed

Properties for 1-Stearoyl-2-Arachidonoyl PC

Molecular Weight:

810.13 g·mol−1

Boiling point:

78° C

Solubility:

Soluble in 1: 2 solution of ethanol: PBS (pH 7.2) (~0.3 mg/ml), DMSO (sparingly), and DMF (sparingly).

Safety & Transport Information

Risk Codes:

R20 - Harmful by inhalation
R22 - Harmful if swallowed
R36/38 - Irritating to eyes and skin
R38 - Irritating to skin
R40 - Limited evidence of a carcinogenic effect
R48/20/22 - Harmful: danger of serious damage to health by prolonged exposure through inhalation and if swallowed
R63 - Possible risk of harm to the unborn child
R67 - Vapours may cause drowsiness and dizziness

Safety Codes:

S26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice
S36/37 - Wear suitable protective clothing and gloves

Hazard Symbols: