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Stauprimide

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Formula: C35H28N4O5
CAS: 154589-96-5
search Element: stauprimide
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Identification

Structural Formula
Stauprimide
CAS:
154589-96-5
EINECS:
Molecular Formula:
C35H28N4O5
MDL:
MFCD14635443
SMILES:
C[C@@]12[C@@H]([C@@H](C[C@@H](O1)N3C4=CC=CC=C4C5=C6C(=C7C8=CC=CC=C8N2C7=C53)C(=O)NC6=O)N(C)C(=O)C9=CC=CC=C9)OC
Synonym:


Description

Stauprimide is an indolocarbazole semi-synthetic small molecule shown to significantly increase the efficiency of directed embryonic stem cell differentiation. Stauprimide inhibits the nuclear localization of NME2, blocking and downregulating c-Myc expression. The expression of c-Myc is crucial for embryonic stem cell self-renewal, and intervention by Stauprimide allows for more efficient lineage-specific differentiation. NME2 is also indicated to be upregulated in certain cancers, indicating further application for the blocking action of Stauprimide.


Suppliers

Indofine Chemical Co, Inc.
Bio-959
Santa Cruz Biotechnology, Inc.
202346
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Prices & Availability




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Properties for Stauprimide

Molecular Weight:
584.6 g·mol−1
Density:
1.53 g/cm3 (Predicted)
Melting point:
227-240°C
Solubility:
Soluble in ethanol (slightly), methanol, DMSO (100 mg/ml), DMF, and water (limited).
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Safety & Transport Information

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Alternative Distributors of [Stauprimide]

Producers or manufacturers change the product range from time to time. The following companies
have appeared as suppliers in the past / currently not verified

Cfm Oskar Tropitzsch GmbH | Fermentek Ltd.

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Mol File:
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MSDS:
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