Stat3 Inhibitor V, Stattic is a small molecule shown to selectively inhibit the activation of the Stat3 transcription factor by blocking phosphorylation and dimerization events. Stattic has been used as a tool for probing the upstream activation of this factor, significantly expressed in many cancer cell lines, and interruption of this pathway in breast cancer cell lines lead to an increased apoptotic rate in these cells. Stat3 Inhibitor V, Stattic is an inhibitor of Stat3.
Specific target organ toxicity following single exposure, category 3
- Respiratory tract irritation
- Narcotic effects
Not used
with the "skull and crossbones" pictogram
for skin or eye irritation if:
the "corrosion" pictogram also appears
the "health hazard" pictogram is used to indicate respiratory sensitization
Safety & Transport Information
Risk Codes:
R20/21/22 - Harmful by inhalation, in contact with skin and if swallowed R22 - Harmful if swallowed R36/37/38 - Irritating to eyes, respiratory system and skin
Safety Codes:
S26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice S36/37/39 - Wear suitable protective clothing, gloves and eye/face protection
Hazard Symbols:
Xi, Xn
Storage temperature :
Store at +4 °C
x
Alternative Distributors of [Stat3 inhibitor V, stattic]
Producers or manufacturers change the product range from time to time. Currently there are no other manufacturers known.