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Smoothened Agonist, HCl

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Formula: C28H28ClN3OS . 2HCl . 2H2O
CAS: 364590-63-6
search Element: smoothened agonist
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Identification

Structural Formula
Smoothened Agonist, HCl
CAS:
364590-63-6
EINECS:
Molecular Formula:
C28H28ClN3OS . 2HCl . 2H2O
MDL:
SMILES:
CNC1CCC(CC1)N(CC2=CC=CC(=C2)C3=CC=NC=C3)C(=O)C4=C(C5=CC=CC=C5S4)Cl.O.Cl.Cl
Synonym:


Description

Smoothened Agonist, HCl (SAG), is a highly potent activator of Smo (smoothened). This chlorobenzothiophene compound is a hedgehog pathway agonist that interacts with the heptahelical domain of Smo. SAG is shown to act as an activator at low concentrations, but can inhibit Smo coupling at very high concentrations. The activating effects of SAG will counteract Cyclopamine or Cyclopamine-KAAD inhibition of Smo.


Suppliers

Santa Cruz Biotechnology, Inc.
202814
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Properties for Smoothened Agonist, HCl

Molecular Weight:
562.98 g·mol−1
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Alternative Distributors of [Smoothened Agonist, HCl]

Producers or manufacturers change the product range from time to time. Currently there are no other manufacturers known.
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