SIRT2 Inhibitor, Inactive Control, AGK7 | CAS 304896-21-7

Element: inhibitor inactive control sirt2 agk7

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Identification

SIRT2 Inhibitor, Inactive Control, AGK7

CAS:

304896-21-7

EINECS:

Molecular Formula:

C₂₃H₁₃Cl₂N₃O₂

MDL:

SMILES:

C1=CC2=C(C(=C1)NC(=O)/C(=C/C3=CC=C(O3)C4=C(C=CC(=C4)Cl)Cl)/C#N)N=CC=C2

Synonym:

Description

SIRT2 Inhibitor, Inactive Control, AGK7 is a cell-permeable structural isomer of SIRT2(sirtuin 2) Inhibitor, AGK2 that selectively inhibits SIRT3 over SIRT1 and SIRT2 (IC₅₀ = >5 μM, >50 μM and >50 μM for SIRT3, SIRT1 and SIRT2, respectively). SIRT2 Inhibitor, Inactive Control, AGK7 poorly affects both α-synuclein-mediated toxicity and α-Syn aggregation in α-Syn-H4 cells. SIRT2 Inhibitor, Inactive Control, AGK7 is an inhibitor of SIRT1(sirtuin 1) and SIRT3(sirtuin 3).

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Santa Cruz Biotechnology, Inc.

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Properties for SIRT2 Inhibitor, Inactive Control, AGK7

Molecular Weight:

434.3 g·mol−1

Solubility:

Soluble in DMSO (10 mg/ml).

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Alternative Distributors of [SIRT2 Inhibitor, Inactive Control, AGK7]

Producers or manufacturers change the product range from time to time. Currently there are no other manufacturers known.

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MSDS:

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