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Silybin

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Formula: C25H22O10
CAS: 22888-70-6
search Element: silybin
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Identification

Structural Formula
Silybin
CAS:
22888-70-6
EINECS:
245-302-5
Molecular Formula:
C25H22O10
MDL:
MFCD00872186
SMILES:
COC1=C(C=CC(=C1)[C@@H]2[C@H](OC3=C(O2)C=C(C=C3)[C@@H]4[C@H](C(=O)C5=C(C=C(C=C5O4)O)O)O)CO)O
Synonym:
flavobin ; 7c3mt ; silybin a ; silibinin ; silymarin ; silybine ; silliver ; silymrin ; silybin ; sylibin


Description

Silybin is an inhibitor of a wide variety of proteins, many of which are heavily involved in xenobiotic efflux and metabolism. Silybin is an inhibitor of P-glycoprotein-mediated cellular efflux and also inhibits xenobiotic oxidation by the CYP (cytochrome P450) superfamily of enzymes. This helps to contribute the apoptotic activity of this compound, which has been shown to be effective against a wide variety of cancer cell lines. Silybin is an inhibitor of 5-LO.


Suppliers

Ambeed, Inc.
A177518
+
Indofine Chemical Co, Inc.
021040
X´ian Taicheng Chem Co., Ltd
XTC203812
+
CSNpharm, Inc.
CSN16195
Carbone Scientific Co., Ltd.
CS196588
+
CM Fine Chemicals
CFC119476
Xingrui Industry Co., Limited
XIL203812
+
BOC Sciences
BS84252
+
Santa Cruz Biotechnology, Inc.
202812
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Chemlyte Solutions
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Arcadia Biotechnology
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Marcor Development Corporation
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Sinogreat Enterprise Ltd.
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FUDAW INDUSTRY LTD
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Aozeal Certified Standards (AOCS), Inc.
S0022.00
Silymarin, water soluble
Salsbury Chemicals, Inc.
SC17285184
(2R,3R)-3,5,7-Trihydroxy-2-((2R,3R)-3-(4-hydroxy-3-methoxyphenyl)-2-(hydroxymethyl)-2,3-dihydrobenzo[b][1,4]dioxin-6-yl)chroman-4-one
BLD Pharmatech Ltd
BP50274150822

Prices & Availability




Data is processed


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Properties for Silybin

Molecular Weight:
482.44 g·mol−1
Melting point:
164-174 °C
Solubility:
Soluble in 100% ethanol (0.1mg/ml), DMSO (10mg/ml), dimethyl formamide (20mg/ml), acetone or methanol; 0.5mg/ml soluble in a 1:9 solution of dimethyl formamide:PBS (pH 7.2) (dilute the dimethyl formamide solution with PBS).
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Safety & Transport Information

Risk Codes:
R36/37/38 - Irritating to eyes, respiratory system and skin
Safety Codes:
S22 - Do not breathe dust
S24/25 - Avoid contact with skin and eyes
S26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice
S36 - Wear suitable protective clothing
S37/39 - Wear suitable gloves and eye/face protection
Hazard Symbols:
Xi
Hazard symbol Xi
Storage temperature :
-20°C
RID/ADR certification :
3172
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Alternative Distributors of [Silybin]

Producers or manufacturers change the product range from time to time. The following companies
have appeared as suppliers in the past / currently not verified

Shanghai Eagle Chemical Co., Ltd. | ABCR GmbH & Co. KG | Chengdu Biopurify Phytochemicals Ltd. | AK Scientific, Inc. | Shanghai Tauto Biotech Co., Ltd. | Chengdu Qiaofeng Technological Development Co., Ltd. | Shanghai Brightol International Co., Ltd. | Carl Roth GmbH + Co KG | Chengdu Conut Intl. Co., Ltd. | Cfm Oskar Tropitzsch GmbH | Greenlife Biotechnology Co.,Ltd. | Changzhou Sunsanta Trading Co., Ltd | Jinan Haohua Industry Co., Ltd. | Hangzhou Dayangchem Co. Ltd.

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MSDS:
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