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Senktide

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Formula: C40H55N7O11S
CAS: 106128-89-6
search Element: senktide
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Identification

Structural Formula
Senktide
CAS:
106128-89-6
EINECS:
Molecular Formula:
C40H55N7O11S
MDL:
MFCD00076799
SMILES:
CC(C)C[C@@H](C(=O)N[C@@H](CCSC)C(=O)N)NC(=O)CNC(=O)[C@H](CC1=CC=CC=C1)N(C)C(=O)[C@H](CC2=CC=CC=C2)NC(=O)[C@H](CC(=O)O)NC(=O)CCC(=O)O
Synonym:
senktide (6-11) ; suc-asp-phe-n-me-phe-gly-leu-met-nh2 ; suc-df-(nmef)-glm-nh2 ; senktide ; suc-[asp6,mephe8]substance p(6-11) ; m.w. 842.1 c40h55n7o11s ; [succinyl-asp6,me-phe8] substance p ; succinyl(asp6 ; senktide trifluoroacetate salt ; suc-df(me)fglm-nh2


Description

Senktide is shown to selectively interact with a tachykinin receptor subtype (SP-N) and can be used in studies to find out the regulation, distribution, and functional role of this receptor. This compound is also reported to be an NK-3R agonist and may cause behavior similar to serotonergic stimulation in murine models. NK-3R (tachykinin NK-3 receptors) have been noted to mediate bronchoconstriction in guinea pig lungs, and activation of these receptors by Senktide has also been shown to induce bronchoconstriction. Furthermore, this agent has demonstrated the ability to induce increased numbers of Fos-LI neurons in numerous regions of the guinea pig brain.


Suppliers

Acinopeptide Co., Ltd.
A176352
Santa Cruz Biotechnology, Inc.
201174
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CAS equal suppliers

Succinyl-(Asp6,N-Me-Phe8)-Substance P (6-11)
Bachem AG
H-5600.0001

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Properties for Senktide

Molecular Weight:
841.97 g·mol−1
Density:
1.29 g/cm3
Boiling point:
1262.64° C at 760 mmHg
Solubility:
Soluble in methanol (25 mg/ml), ethanol (25 mg/ml), and DMSO (25 mg/ml).
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Safety & Transport Information

Storage temperature :
-20°C
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Alternative Distributors of [Senktide]

Producers or manufacturers change the product range from time to time. Currently there are no other manufacturers known.
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Downloads

Mol File:
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MSDS:
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