[Sar-9, Met(O2)-11]-Substance P | CAS 110880-55-2

Element: substance

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Identification

[Sar-9, Met(O2)-11]-Substance P

CAS:

110880-55-2

EINECS:

Molecular Formula:

C₆₄H₁₀₀ N₁₈ O₁₅ S

MDL:

MFCD00076787

SMILES:

CC(C)CC(C(=O)NC(CCS(=O)(=O)C)C(=O)N)NC(=O)CN(C)C(=O)C(CC1=CC=CC=C1)NC(=O)C(CC2=CC=CC=C2)NC(=O)C(CCC(=O)N)NC(=O)C(CCC(=O)N)NC(=O)C3CCCN3C(=O)C(CCCCN)NC(=O)C4CCCN4C(=O)C(CCCN=C(N)N)N

Synonym:

bhsar-sp ; [sar9]sp sulphone ; [sar9,met(o2)11]sp ; [sar9, met(o2)11 ; [sar9,met(o2)11]substance p ; substance p,9-(n-methylglycine)-11-[(2s)-2-amino-4-(methylsulfonyl)butanamide]- (9ci) ; rpkpqqffsarlm(o2) ; substance p,9-(n-methylglycine)-11-(s,s-dioxido-l-methioninamide)- ; homspera ; viprovex ; substance p, 9-(n-methylglycine)-11-[4-(methylsulfonyl)-l-2-aminobutanamide]- ; (sar9,met(o2)11)-substance p ; 65: pn: us20050009742 page: 20claimed sequence ; [sar9]substance p sulphone ; [sar9]sp sulfone ; 9-sar-11-met(o2)-substance p ; 9-sar-substance p sulfone ; 11: pn: wo2009085236 page: 39 claimed protein

Description

Sar-9, Met(O2)-11]-Substance P is a highly selective NK-1R (NK-1 neurokinin receptor) agonist which stimulates endocytosis of NK-1 receptors but has minimal effect on NK-3 receptors. Studies suggest that this peptide does not insert into neutral or negatively charged lipid bilayers and densely packed lipid monolayers at surface pressures greater than 31 mN/m. Furthermore, in vitro tests show that Sar-9, Met(O2)-11]-Substance P augments the release of vasopressin from the hypothalamo-neurohypophysial system.

Suppliers

Santa Cruz Biotechnology, Inc.

201170

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CAS equal suppliers

(SAR9,MET(O2)11)-SUBSTANCE P

Bachem AG

H-9410.0001

(SAR9,MET(O2)11)-SUBSTANCE P

Acinopeptide Co., Ltd.

A30806160

(Sar9,Met(O2)11)-Substance P

Santa Cruz Biotechnology, Inc.

SCB420016800

(Sar9,Met(O2)11)-Substance P

BOC Sciences

BS16805040

Prices & Availability

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Properties for [Sar-9, Met(O2)-11]-Substance P

Molecular Weight:

1393.66 g·mol−1

Density:

1.43 g/cm3

Safety & Transport Information

Storage temperature :

-20°C

Alternative Distributors of [[Sar-9, Met(O2)-11]-Substance P]

Producers or manufacturers change the product range from time to time. The following companies
have appeared as suppliers in the past / currently not verified

Chem-Impex International, Inc. | Shanghai Hanhong Chemical Co., Ltd.