Sanguinarine chloride | CAS 5578-73-4

Element: sanguinarine chloride

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C-S » Chemicals » sanguinarine-chloride-PX245147

Identification

Sanguinarine chloride

CAS:

5578-73-4

EINECS:

Molecular Formula:

C₂₀H₁₄NO₄Cl

MDL:

MFCD00012126

SMILES:

C[N+]1=C2C(=C3C=CC4=C(C3=C1)OCO4)C=CC5=CC6=C(C=C52)OCO6.[Cl-]

Synonym:

pseudochelerythrine ; sanguinarine hcl ; sanguinarium ; sanguinarin-chlorid 97% ; sanguinarine chloride ; speciociliatine(sh) ; sanguinarine hcl hplc ; sanguinariumchloride ; sanguinarine(sh) ; viadent

Description

Sanguinarine chloride is a benzophenanthridine alkaloid and potent, noncompetitive sodium/Potassium-ATPase Protein Inhibitors (Na+/K+ ATPase) inhibitor with anticancer properties. This product has been observed to induce apoptosis in cultured C6 rat glioblastoma cells potentially via a downregulative ability of extracellular singal-regulated and Akt signaling pathways. It is reported that sanguinarine also inhibits protein phosphatase 2C (PP2) and induces human promyelocytic leukemia cell line HL60 apoptosis through the phosphorylation of p38, a PP2Cα substrate associated with caspase-3/7 activity. This compound posesses antimicrobial and anti-plaque qualities. Sanguinarine chloride is an inhibitor of MKP-1 and PP2.

Suppliers

H&Z Industry Co.,Ltd

HIC8403360

Autech Industry Co.,Limited

AIC11344536

Indofine Chemical Co, Inc.

021845

CSNpharm, Inc.

CSN11892

Finetech Industry Limited

FIL10504200

Pharmacore Co., Limited

PL9662898

AK Scientific, Inc.

AS7982394

Leap Chem Co., Ltd

LC7562268

Santa Cruz Biotechnology, Inc.

202800

Dayang Chem (Hangzhou) Co.,Ltd.

DC13025208

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CAS equal suppliers

5-Chlorpyrimidin-2-amin

Finetech Industry Limited

FIL11504600

Prices & Availability

Data is processed

Properties for Sanguinarine chloride

Molecular Weight:

367.78 g·mol−1

Melting point:

281-285 °C

Solubility:

methanol: 20 mg/mL, clear, orange

Safety & Transport Information

Risk Codes:

R22 - Harmful if swallowed

Safety Codes:

S26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice
S36 - Wear suitable protective clothing

Hazard Symbols:

Storage temperature :

Store at +4 °C

Alternative Distributors of [Sanguinarine chloride]

Producers or manufacturers change the product range from time to time. The following companies
have appeared as suppliers in the past / currently not verified

Cfm Oskar Tropitzsch GmbH | BOC Sciences | ABCR GmbH & Co. KG | Trademax Phamaceuticals & Chemicals Co., Ltd. | Clearsynth Canada INC.

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