Salermide | CAS 1105698-15-4 | Chemical-Suppliers

Element: salermide

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C-S » Chemicals » salermide-PX58890

Identification

Salermide

CAS:

1105698-15-4

EINECS:

Molecular Formula:

C₂₆H₂₂N₂O₂

MDL:

MFCD12912446

SMILES:

CC(C1=CC=CC=C1)C(=O)NC2=CC=CC(=C2)NC=C3C(=O)C=CC4=CC=CC=C43

Synonym:

Description

Salermide is a reverse amide with strong inhibitory effects on SIRT1 (Sirtuin 1) and SIRT2 (Sirtuin 2). SIRT1/2 both belong to the family of NAD⁺-dependent class III histone deacetylases and are shown to target protein 53, a cell cycle regulator. Salermide is shown to induce acetylation of p53 and cause cell apoptosis. Salermide also inhibits members of HDAC3 (class III HDACs).

Suppliers

Ambeed, Inc.

A557147

Aea.ltd

A63126

CSNpharm, Inc.

CSN18937

Santa Cruz Biotechnology, Inc.

224276

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Prices & Availability

Data is processed

Properties for Salermide

Molecular Weight:

394.47 g·mol−1

Density:

~1.16 g/cm³ (Predicted)

Boiling point:

~666.67° C at 760 mmHg (Predicted)

Solubility:

Soluble in DMSO (100 mM), DMF (~30 mg/ml), and DMSO : PBS (pH 7.2)(1:2) (~0.25 mg/ml).

Safety & Transport Information

coming up soon

Alternative Distributors of [Salermide]

Producers or manufacturers change the product range from time to time. The following companies
have appeared as suppliers in the past / currently not verified

Jinjiangchem Corporation | D&P Global Chemical Co., Ltd

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Mol File:

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MSDS:

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