Rosiglitazone (potassium salt) | CAS 316371-84-3

Element: rosiglitazone potassium salt

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C-S » Chemicals » rosiglitazone-potassium-salt-PX68202

Identification

Rosiglitazone (potassium salt)

CAS:

316371-84-3

EINECS:

Molecular Formula:

C₁₈H₁₈N₃O₃S.K

MDL:

MFCD12912358

SMILES:

CN(CCOC1=CC=C(C=C1)CC2C(=O)NC(=O)S2)C3=CC=CC=N3.[K]

Synonym:

rosiglitazonepotassiumsalt

Description

Rosiglitazone (potassium salt) is a PPARγ (peroxisome proliferator-activated subtype gamma receptor) agonist which regulates the epithelial sodium channel (ENaC) and Na-K-2Cl (NKCC2) co-transporter. Studies have shown that NKCC2 is inhibited by down regulation of the genes that code for the protein. Further studies have shown that Rosiglitazone increases the abundance of the α subunit of ENaC but causes a decrease in the abundance of cortical β- and γ-ENaC.

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Santa Cruz Biotechnology, Inc.

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Properties for Rosiglitazone (potassium salt)

Molecular Weight:

395.522 g·mol−1

Solubility:

Soluble in ethanol (~2 mg/ml), DMSO (~25 mg/ml), DMF (~25 mg/ml), and water (500 µg/ml at 25° C).

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Alternative Distributors of [Rosiglitazone (potassium salt)]

Producers or manufacturers change the product range from time to time. Currently there are no other manufacturers known.

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