Rosiglitazone | CAS 122320-73-4 | Chemical-Suppliers

Element: rosiglitazone

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C-S » Chemicals » rosiglitazone-PX76670

Identification

Rosiglitazone

CAS:

122320-73-4

EINECS:

Molecular Formula:

C₁₈H₁₉N₃O₃S

MDL:

MFCD00871760

SMILES:

CN(CCOC1=CC=C(C=C1)CC2C(=O)NC(=O)S2)C3=CC=CC=N3

Synonym:

avandia ; roeiglitazonemaleate ; rosigliazone ; brl 49653 ; rosiglitazonehcl ; rosiglitazone, >=98.5% ; roiglitazone ; rosiglitazone hcl ; rosiglitazone ; rosiglitazone 99%

Description

Rosiglitazone is a potent, selective PPARγ (Peroxisome proliferator-activated receptor) agonist (K_d= 43 nM) which exhibits anti-diabetic and hepatotoxic effects. PPARγ belongs to a group of nuclear receptor proteins that are essential to the regulation of cellular differentiation, development and metabolism, and plays a functional role in adipogenesis. Studies also suggest that natural PPARγ agonists found in foods may be beneficial ant-inflammatory agents. Rosiglitazone, also known as BRL 49653, is a thiazolidinedione derivative effective in increasing insulin sensitivity in muscle and adipose tissue, as well as inducing adipocyte differentiation in pluripotent C3H10T1/2 stem cells.

Suppliers

Ambeed, Inc.

A158185

Aozeal Certified Standards (AOCS), Inc.

R0017.00

Shandong Ench Chemical Co.,Ltd

SECC3901950

H&Z Industry Co.,Ltd

HIC2601040

Autech Industry Co.,Limited

AIC3511404

Conscientia Industrial Co., Ltd (Zhejiang Conscientia Pharmaceutical)

CI8973588

Chemlyte Solutions

CS234702

Xiamen Equation Chemical Co.,Ltd

XECC4162080

CSNpharm, Inc.

CSN12512

Wanko Chemical Co., Ltd.

WC312936

Carbone Scientific Co., Ltd.

CS3641092

Hefei Hirisun Pharmatech Co., Ltd

HR012623

CM Fine Chemicals

CFC221884

AK Scientific, Inc.

AS247741

Capot Chemical Co., Ltd.

44722

Leap Chem Co., Ltd

LC234702

Santa Cruz Biotechnology, Inc.

202795

Dayang Chem (Hangzhou) Co.,Ltd.

DC4031612

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CAS equal suppliers

Rosiglitazone Succinate

LGM Pharma

LP4601380

Rosiglitazone Succinate

Jiwan Pharmaceutical Technology Co., Ltd.

JPT18867544

5-(4-(2-(Methyl(pyridin-2-yl)amino)ethoxy)benzyl)thiazolidine-2,4-dione

Hangzhou MolCore BioPharmatech Co.,Ltd.

CS13559

5-[[4-[2-(Methyl-2-pyridinylamino)ethoxy]-phenyl]methyl]-2,4-thiazolidine-dione

Xingrui Industry Co., Limited

XIL2291091640

5-[[4-[2-(Methyl-2-pyridinylamino)ethoxy]-phenyl]methyl]-2,4-thiazolidine-dione

Gihi Chemicals Co., Limited

GCL2133085320

5-[[4-[2-(Methyl-2-pyridinylamino)ethoxy]-phenyl]methyl]-2,4-thiazolidine-dione

BLD Pharmatech Ltd

BP1422042660

Prices & Availability

Data is processed

Properties for Rosiglitazone

Molecular Weight:

357.43 g·mol−1

Density:

1.32 g/cm³ (Predicted)

Melting point:

153-155 C

Boiling point:

584.98° C at 760 mmHg (Predicted)

Solubility:

Soluble in DMSO (72 mg/ml at 25° C), methanol, water (<1 mg/ml at 25° C), ethanol (<1 mg/ml at 25° C), and DMF (~25 mg/ml).

Safety & Transport Information

Risk Codes:

R36/38 - Irritating to eyes and skin

Safety Codes:

S26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice
S37/39 - Wear suitable gloves and eye/face protection

Hazard Symbols:

Storage temperature :

2-8 °C

Alternative Distributors of [Rosiglitazone]

Producers or manufacturers change the product range from time to time. The following companies
have appeared as suppliers in the past / currently not verified