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Retrorsine

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Formula: C18H25NO6
CAS: 480-54-6
search Element: retrorsine
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Identification

Structural Formula
Retrorsine
CAS:
480-54-6
EINECS:
Molecular Formula:
C18H25NO6
MDL:
SMILES:
C/C=C1/C[C@H]([C@@](C(=O)OCC2=CCN3[C@H]2[C@@H](CC3)OC1=O)(CO)O)C
Synonym:
retrorsin ; retrorsine ; 16-dione,12,18-dihydroxy-senecionan-1 ; cis-retronecicacidesterofretronecine ; retrosine ; beta-longilobine ; β-longilobine ; retrorcine ; retrorsine(as) ; 12,18-dihydroxysenecionan-11,16-dione


Description

Retrorsine, a pyrrolizidine alkaloid, is a mutagenic, antimitotic, and cytotoxic compound. The toxicity of retrorsine relies on its bioactivation by cytochrome P450 enzymes (CYP). The toxicity of retrorsine has been shown to result from one of two compounds that are generated after CYP metabolism of retrorsine.


Suppliers

Conscientia Industrial Co., Ltd (Zhejiang Conscientia Pharmaceutical)
CI6902760
+
Sigma-Aldrich International GmbH
SI320960
+
Finetech Industry Limited
FIL2501000
+
Carbone Scientific Co., Ltd.
CS280840
+
Leap Chem Co., Ltd
LC180540
+
Santa Cruz Biotechnology, Inc.
215805
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CAS equal suppliers

Retrorsin
Excenen Pharmatech Co., Ltd.
EN-8319

Prices & Availability




Data is processed


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Properties for Retrorsine

Molecular Weight:
351.39 g·mol−1
Density:
1.32 ±0.1 g/cm3 (20 °C 760 Torr)
Melting point:
208-211 °C(lit.)
Solubility:
Soluble in Chloroform (25 mg/ mL) and ethanol
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Safety & Transport Information

Risk Codes:
R25 - Toxic if swallowed
Safety Codes:
S22 - Do not breathe dust
S36/37/39 - Wear suitable protective clothing, gloves and eye/face protection
S45 - In case of accident or if you feel unwell seek medical advice immediately (show the label where possible)
Hazard Classes:
6.1(a)
Hazard Symbols:
T
Hazard symbol T
Storage temperature :
?20 °C
RID/ADR certification :
1544
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Alternative Distributors of [Retrorsine]

Producers or manufacturers change the product range from time to time. The following companies
have appeared as suppliers in the past / currently not verified

Carl Roth GmbH + Co KG | Cfm Oskar Tropitzsch GmbH | Clearsynth Canada INC.

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Downloads

Mol File:
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MSDS:
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