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Ramiprilat Diketopiperazine

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Formula: C21H26N2O4
CAS: 108736-10-3
search Element: diketopiperazine ramiprilat
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Identification

Structural Formula
Ramiprilat Diketopiperazine
CAS:
108736-10-3
EINECS:
Molecular Formula:
C21H26N2O4
MDL:
SMILES:
[2H]C1=C(C(=C(C(=C1[2H])[2H])CC[C@H](C(=O)O)N2[C@H](C(=O)N3[C@H]4CCC[C@H]4C[C@H]3C2=O)C)[2H])[2H]
Synonym:
ramiprilat diketopiperazine (mixture of diastereoisomers) ; [3s-[2(r*),3a,5ab,8ab,9ab]]-decahydro-3-methyl-1,4-dioxo-a-(2-phenylethyl)-2h-cyclopenta[4,5]pyrrolo[1,2-a]pyrazine-2-acetic acid ; [3s-[2(r*),3α,5aβ,8aβ,9aβ]]-decahydro-3-methyl-1,4-dioxo-α-(2-phenylethyl)-2h-cyclopenta[4,5]pyrrolo[1,2-a]pyrazine-2-acetic acid ; ramiprilat diketopiperazine ; [3s-[2(r*),3a,5a,8a,9a]]-decahydro-3-methyl-1,4-dioxo-a-(2-phenylethyl)-2h-cyclopenta[4,5]pyrrolo[1,2-a]pyrazine-2-acetic acid ; (αs,3s,5as,8as,9as)-decahydro-3-methyl-1,4-dioxo-α-(2-phenylethyl)- 2h-cyclopenta[4,5]pyrrolo[1,2-a]pyrazine-2-acetic acid ; ramipril diketopiperazine acid ; ramipril impurity – k (ep) ; ramipril ep impurity k


Description

Ramiprilat Diketopiperazine is a metabolite of Ramiprilat. Ramiprilat is the active metabolite of Ramipril. Ramipril is an inhibitor of the angiotensin- converting enzyme (ACE) that is reported to quickly hydrolyze into Ramiprilat. Studies indicate that Ramipril is a more potent inhibitor in comparison to Zofenopril (sc-208496). Acute coronary syndrome investigations demonstrate that Ramipril increases IL-10, and decreases the levels of MCP-1 and IL-18. Ramiprilat has been reported to bind to ACE on the surface of endothelial cells and activate cell-specific signaling, which includes induction of the activator protein (AP)-1.


Suppliers

Santa Cruz Biotechnology, Inc.
212768
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CAS equal suppliers

Ramipril EP Impurity K
Aozeal Certified Standards (AOCS), Inc.
R0002.11
2-(5-Methyl-4,7-dioxo-decahydro-3b,6-diaza-cyclopenta[a]inden-6-yl)-4-phenyl-butyric acid
Pharmaffiliates Analytics & Synthetics Pvt. Limited
PA 18 05110

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Properties for Ramiprilat Diketopiperazine

Molecular Weight:
370.44 g·mol−1
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Alternative Distributors of [Ramiprilat Diketopiperazine]

Producers or manufacturers change the product range from time to time. Currently there are no other manufacturers known.
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MSDS:
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