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Quercetagetin

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Formula: C15H10O8
CAS: 90-18-6
search Element: quercetagetin
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Identification

Structural Formula
Quercetagetin
CAS:
90-18-6
EINECS:
201-973-6
Molecular Formula:
C15H10O8
MDL:
MFCD00017428
SMILES:
C1=CC(=C(C=C1C2=C(C(=O)C3=C(C(=C(C=C3O2)O)O)O)O)O)O
Synonym:
3,3',4',5,6,7-hexahydroxyflavone ; 3,5,6,7-tetrahydroxy-2-(3,4-dihydroxyphenyl)-4h-1-benzopyran-4-one ; quercetagenin ; quercetagin ; 6,7,4'-quercetagetin ; quercetagetin ; 3,5,6,7,3',4'-hexahydroxyflavone ; 6-hydroxyquercetin ; 2-(3,4-dihydroxyphenyl)-3,5,6,7-tetrahydroxy-4-benzopyrone ; quebrachitol, (-)-(rg)


Description

Quercetagetin is a cell-permeable flavanol compound that acts a potent, ATP-competitive, and reversible inhibitor of PIM1 kinase (IC50 = 340 nM). Exhibits ≥7-fold selectivity over 8 other kinases tested, including PIM2 (IC50 = 3.45 µM), and little activity toward c-Abl even at concentrations as high as 200 µM. Inhibits cellular BAD phosphorylation (IC50 = 5.5 µM) and induces growth arrest (ED50 = 3.8 µM) in PIM1-expressing RWPE2 cells.


Suppliers

Indofine Chemical Co, Inc.
021030
Santa Cruz Biotechnology, Inc.
204221
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CAS equal suppliers

Quercetagenin
Hangzhou J&H Chemical Co., Ltd.
HJC4031612
Quercetagenin
Santa Cruz Biotechnology, Inc.
SCB3901560

Prices & Availability




Data is processed


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Properties for Quercetagetin

Molecular Weight:
318.24 g·mol−1
Density:
~1.9 g/cm3 (Predicted)
Melting point:
>300 °C
Boiling point:
~732.4° C at 760 mmHg (Predicted)
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Safety & Transport Information

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Alternative Distributors of [Quercetagetin]

Producers or manufacturers change the product range from time to time. The following companies
have appeared as suppliers in the past / currently not verified

Chengdu Qiaofeng Technological Development Co., Ltd.

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MSDS:
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