N-(3-Pyridyl)indomethacin Amide | CAS 261755-29-4

Element: indomethacin pyridyl amide

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C-S » Chemicals » pyridyl-indomethacin-amide-PX71517

Identification

N-(3-Pyridyl)indomethacin Amide

CAS:

261755-29-4

EINECS:

Molecular Formula:

C₂₄H₂₀ClN₃O₃

MDL:

SMILES:

CC1=C(C2=C(N1C(=O)C3=CC=C(C=C3)Cl)C=CC(=C2)OC)CC(=O)NC4=CN=CC=C4

Synonym:

Description

N-(3-Pyridyl)indomethacin Amide is a potent and selective reversible Cox-2 (cyclooxygenase-2) inhibitor (IC₅₀ of 0.1 μM for human recombinant) and is about 300-fold less potent as an inhibitor of human recombinant Cox-1. N-(3-Pyridyl)indomethacin Amide is not as selective with natural ovine Cox (IC₅₀ of 75 μM for Cox-1 and IC₅₀ of 50 μM for Cox-2).

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Santa Cruz Biotechnology, Inc.

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Properties for N-(3-Pyridyl)indomethacin Amide

Molecular Weight:

433.89 g·mol−1

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Alternative Distributors of [N-(3-Pyridyl)indomethacin Amide]

Producers or manufacturers change the product range from time to time. Currently there are no other manufacturers known.

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MSDS:

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