Pyrazolylpyrrole ERK Inhibitor | CAS 933786-58-4

Element: pyrazolylpyrrole inhibitor

Page Content Identification Properties Suppliers Prices & Availability Get Quick Quote ☰

Identification Properties Suppliers Prices & Availability Get Quick Quote

C-S » Chemicals » pyrazolylpyrrole-erk-inhibitor-PX78984

Identification

Pyrazolylpyrrole ERK Inhibitor

CAS:

933786-58-4

EINECS:

Molecular Formula:

C₂₂H₁₇Cl₂FN₄O₂

MDL:

SMILES:

C1=CC(=CC(=C1)Cl)C2=CNNC2=C3C=C(N=C3)C(=O)NC(CO)C4=CC(=C(C=C4)F)Cl

Synonym:

cay10561 exclusive ; pyrazolylpyrrole erk inhibitor ; cay10561

Description

Pyrazolylpyrrole ERK Inhibitor is a potent, ATP-competitive inhibitor of ERK2 (K_i = 2 nM). This compound is highly selective for ERK2 compared to other kinases such as PKA (K_i = 0.39 µM) and JNK3 (K_i = 4 µM). Inhibits proliferation of Colo205 cells with an IC₅₀ value of 0.54 µM.

Suppliers

Santa Cruz Biotechnology, Inc.

222229

Get Quick Quote

CAS equal suppliers

N-[1-(3-Chloro-4-fluorophenyl)-2-hydroxyethyl]-4-[4-(3-chlorophenyl)-1,2-dihydropyrazol-3-ylidene]pyrrole-2-carboxamide

Chemlyte Solutions

CS3213096390

Prices & Availability

Data is processed

Properties for Pyrazolylpyrrole ERK Inhibitor

Molecular Weight:

459.30 g·mol−1

Solubility:

Soluble in 1:1 ethanol:PBS (pH 7.2) (~0.5 mg/ml), ethanol (~ 5 mg/ml), DMSO (~ 1.5 mg/ml), and DMF (~ 2.5 mg/ml).

Safety & Transport Information

coming up soon

Alternative Distributors of [Pyrazolylpyrrole ERK Inhibitor]

Producers or manufacturers change the product range from time to time. Currently there are no other manufacturers known.

Downloads

Mol File:

-/-

MSDS:

-/-