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Pyrazole N-Demethyl Sildenafil

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Formula: C21H28N6O4S
CAS: 139755-95-6
search Element: sildenafil demethyl pyrazole
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Identification

Structural Formula
Pyrazole N-Demethyl Sildenafil
CAS:
139755-95-6
EINECS:
Molecular Formula:
C21H28N6O4S
MDL:
SMILES:
CCOc1ccc(cc1c1[nH]c(=O)c2[nH]nc(CCC)c2n1)S(=O)(=O)N1CCN(C)CC1
Synonym:
pyrazole n-demethyl sildenafil ; 1-[[3-(4,7-dihydroxy-7-oxo-3-propyl-1h-pyrazolo[4,3-d]pyrimidin-5-yl)-4-ethoxyphenyl]sulfonyl]-4-methyl-piperazine


Description

Pyrazole N-Demethyl Sildenafil is an analog of Sildenafil. Sildenafil is a selective inhibitor of the type 5 cGMP phosphodiesterase (PDE5 inhibitor) which catalyzes the hydrolysis of 3',5'-cyclic guanosine monophosphate (cGMP). As a PDE5 inhibitor, Sildenafil has been reported to enhance neuro-, synapto- and angiogenesis in rat models of stroke and also is reported to be a mild vasodilator. Sildenafil has also been shown to prevent indomethacin-induced small intestinal ulceration formation through an NO/cGMP- dependent mechanism.


Suppliers

Santa Cruz Biotechnology, Inc.
212604
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CAS equal suppliers

Pyrazole N-Desmethyl Sildenafil
Aozeal Certified Standards (AOCS), Inc.
S0005.33

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Properties for Pyrazole N-Demethyl Sildenafil

Molecular Weight:
460.55 g·mol−1
Melting point:
232-234 °C
Solubility:
Soluble in DMF, DMSO and Methanol
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Safety & Transport Information

Storage temperature :
-20 °C Freezer
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Alternative Distributors of [Pyrazole N-Demethyl Sildenafil]

Producers or manufacturers change the product range from time to time. Currently there are no other manufacturers known.
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Downloads

Mol File:
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MSDS:
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